SMOX

Gene Symbol	SMOX
Entrez Gene	54498
Alt Symbol	C20orf16, PAO, PAO-1, PAO1, PAOH, PAOH1, SMO
Species	Human
Gene Type	protein-coding
Description	spermine oxidase
Other Description	flavin containing amine oxidase|flavin-containing spermine oxidase|polyamine oxidase 1|putative cyclin G1 interacting protein
Swissprots	Q5TE26 Q9BW38 Q5TE27 D3DVZ4 Q9NPY1 Q9H6H1 Q8IX00 A2A2P5 Q96QT3 A2A2P6 Q6UY28 A8BE87 Q96LC4 Q9NWM0 Q9NP51 Q9NPY2 Q96LC3
Accessions	EAX10457 EAX10458 EAX10459 EAX10460 EAX10461 EAX10462 EAX10463 Q9NWM0 AF519179 AAN77119 AK000753 BAA91360 AK025938 BAB15288 AK127286 AK293485 BAG56974 AL162058 CAB82396 AW136764 AY033889 AAK55763 AY033890 AAK55764 AY033891 AAK55765 AY358104 AAQ88471 BC000669 AAH00669 BG480614 BG679874 EF032141 ABM01872 U61836 XM_011529261 XP_011527563 NM_001270691 NP_001257620 NM_175839 NP_787033 NM_175840 NP_787034 NM_175841 NP_787035 NM_175842 NP_787036
Function	Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
Subcellular Location	Isoform 6: Cytoplasm. Nucleus.
Tissue Specificity	Widely expressed. Expressed in human tumor cell lines. Isoform 4 is only found in an embryonal kidney cell line. {ECO:0000269|PubMed:18422650}.
Top Pathways	Arginine and proline metabolism, beta-Alanine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SMOX overexpression lysate - LY406224 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SMOX overexpression lysate - LY406226 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

SMOX overexpression lysate - LY430441 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SMOX 293 Cell Lysate - 403848 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SMOX 293 Cell Lysate - 403849 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SMOX Overexpression Lysate (Native) - NBL1-16249 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SMOX Over-expression Lysate Product - GWB-DF3811 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

SMOX Over-expression Lysate Product - GWB-713186 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human SMOX Knockdown Stable Cell Line - CSC-DC014767 from Creative biogene Category Cell Line Species Human

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