CDCA2

Gene Symbol CDCA2
Entrez Gene 157313
Alt Symbol PPP1R81, Repo-Man
Species Human
Gene Type protein-coding
Description cell division cycle associated 2
Other Description cell division cycle-associated protein 2|protein phosphatase 1 [gamma] (PPP1R3A) binding protein Repo-Man|protein phosphatase 1, regulatory subunit 81|recruits PP1 onto mitotic chromatin at anaphase protein
Swissprots Q69YI4 Q4G0W0 Q69YH5 Q8N7C1 Q6P464 Q3SX74 Q5RKN0
Accessions Q69YH5 AK092164 BAG52490 AK098670 BAC05374 AK292505 BAF85194 AK299278 BAH12991 AL833396 CAH10585 AL833627 CAH10577 BC015691 BC036214 AAH36214 BC063651 AAH63651 BC085609 AAH85609 BC104450 AAI04451 BC104451 AAI04452 BG354575 BG716934 BM802460 BX649008 R95735 XM_005273418 XP_005273475 XM_006716294 XP_006716357 XM_011544415 XP_011542717 XM_011544416 XP_011542718 XM_011544417 XP_011542719 XM_011544418 XP_011542720 XM_011544419 XP_011542721 XM_011544420 XP_011542722 XR_949377 NM_152562 NP_689775
Function Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates. {ECO:0000269|PubMed:16492807, ECO:0000269|PubMed:16998479}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16492807}. Note=Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:16492807}.

Repo-Man (H-300) - sc-134950 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Repo-Man (T-20) - sc-83163 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Repo-Man (V-16) - sc-83164 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CDCA2 antibody - ab45129 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CDCA2 antibody (ab45129) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : HeLa (Human epithelial carcinoma cell line) Nuclear LysateLane 3 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 4 : HepG2 (Human hepatocellular liver carcinoma cell line) Nuclear Lysate (ab14660)Lysates/proteins at 10 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-CDCA2 antibody - ab136137 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CDCA2 antibody (ab136137) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-CDCA2 antibody - ab199615 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CDCA2 antibody (ab199615) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : A431 cell lysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-rabbit IgG H&L(HRP) at 1/5000 dilutiondeveloped using the ECL technique

Anti-CDCA2 Antibody (aa511-560) - LS-C119442 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from 293 cells, using CDCA2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CDCA2 Antibody (aa485-534) - LS-C291778 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CDCA2 Antibody - NBP1-87140 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: CDCA2 Antibody [NBP1-87140] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.

CDCA2 Antibody - NBP1-87139 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDCA2 Polyclonal Antibody - bs-7786R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-CDCA2 Polyclonal Antibody, Unconjugated (bs-7786R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-CDCA2 antibody produced in rabbit - HPA026293 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CDCA2: <B>Cat. No. HPA026293</B>: Immunohistochemical staining of human cerebral cortex shows strong nuclear and nuclear membrane positivity in neurons and glial cells.

Anti-CDCA2 antibody produced in rabbit - HPA030049 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CDCA2: <B>Cat. No. HPA030049</B>: Immunohistochemical staining of human testis shows strong nuclear positivity in seminiferus duct cells.

Anti-CDCA2 antibody produced in rabbit - SAB4500599 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CDCA2: <B>Cat. No. SAB4500599</B>: Immunoblotting analysis of extracts from 293 cells, using Anti-CDCA2 antibody. The lane on the left was treated with the Anti-CDCA2 antibody. The lane on the right (negative control) was treated with both Anti-CDCA2 antibody and the synthesized immunogen peptide.

CDCA2-Antibody - AP50761 from Abgent, a WuXi AppTec company

Prices $295.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from Hela,A431 cell line (from left to right),using CDCA2 Antibody(AP50761). AP50761 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.

CDCA2 antibody - GTX87138 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-CDCA2 antibody used in Western blot. GTX87138

CDCA2 Antibody (OAAB18554) - OAAB18554 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CDCA2 Antibody (OAAF02882) - OAAF02882 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CDCA2 Antibody (OAAF06206) - OAAF06206 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CDCA2 antibody - 70R-16313 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

CDCA2 antibody - 70R-32344 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CDCA2 Antibody - abx013936 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

CDCA2 Antibody - abx121337 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

CDCA2 antibody - 17701-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
HepG2 cells were subjected to SDS PAGE followed by western blot with 17701-1-AP(CDCA2 antibody) at dilution of 1:500

Anti-Repo-Man antibody - STJ95418 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
Search more