KSR2

Gene Symbol	KSR2
Entrez Gene	283455
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	kinase suppressor of ras 2
Other Description	kinase suppressor of Ras 2
Swissprots	A0PJT2 Q6VAB6 Q8N775 Q3B828
Accessions	CAH68720 EAW98111 EAW98112 Q6VAB6 AK098831 BAC05426 AY345972 AAQ24226 BC107106 AAI07107 BC107107 AAI07108 BC127603 AAI27604 BX648958 DW009880 DW009881 XM_011538224 XP_011536526 XM_011538225 XP_011536527 XM_011538226 XP_011536528 XM_011538227 XP_011536529 XM_011538228 XP_011536530 XM_011538229 XP_011536531 XM_011538230 XP_011536532 XR_944522 NM_173598 NP_775869
Function	Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8- mediated signaling. Acts as a negative regulator of MAP3K3- mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. {ECO:0000269|PubMed:12975377, ECO:0000269|PubMed:16039990, ECO:0000269|PubMed:21441910}.
Subcellular Location	Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity	Mainly expressed in brain and kidney. {ECO:0000269|PubMed:12975377}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human KSR2 ELISA Kit (Cell-Based ELISA) - LS-F3239 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 78-5000 pg/ml

Kinase suppressor of Ras 2, KSR2, Human, ELISA Kit - E1806h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 78-5000 pg/mL

KSR2 Colorimetric Cell-Based ELISA - CB6065 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

kinase suppressor of ras 2, ELISA Kit - MBS9326865 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human KSR2 ELISA Kit (Custom ELISA) - LS-F18575 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Mouse KSR2 ELISA Kit (Custom ELISA) - LS-F18576 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Human Kinase suppressor of Ras 2 ELISA Kit - abx251262 from Abbexa Category ELISA Kit Range 78 pg/ml - 5000 pg/ml

KSR2 ELISA Kit - DEIA-XYA1119 from Creative Diagnostics Category ELISA Kit

Human Kinase suppressor of Ras 2 ELISA Kit - EKE51942 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 34 pg/mL Range 78-5000 pg/mL

KSR2 - EKH3882 from Nordic BioSite Sensitivity 46.9pg/ml Range 78-5000pg/ml

Human KSR2 ELISA Kit - E021809 from Biobool Category ELISA Kit Sensitivity <46.9pg/ml

KSR2 ELISA Kit (Human) (OKEH04713) - OKEH04713 from Aviva Systems Biology Category ELISA Kit Prices $425.00 Sizes 96 wells Sensitivity < 39 pg/mL Range 78 - 5,000 pg/mL

Kinase suppressor of Ras 2, ELISA Kit - MBS764990 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.9pg/ml Range 78-5000pg/ml

Kinase suppressor of Ras 2, ELISA Kit - MBS2886749 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 78-5000 pg/mL

Kinase suppressor of Ras 2, ELISA Kit - MBS764571 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Mouse KSR2 ELISA Kit (Sandwich ELISA) - LS-F35333 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.094 Range 78-5000 pg/ml

Human KSR2 ELISA Kit (Sandwich ELISA) - LS-F35332 from LifeSpan Bioscience Category ELISA Kit Sensitivity 46.9 Range 78-5000 pg/ml

KSR2 Colorimetric Cell-Based ELISA Kit - EKA50889 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

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