SRPX2

Gene Symbol SRPX2
Entrez Gene 27286
Alt Symbol BPP, CBPS, PMGX, RESDX, SRPUL
Species Human
Gene Type protein-coding
Description sushi-repeat containing protein, X-linked 2
Other Description sushi repeat-containing protein SRPX2|sushi-repeat protein up-regulated in leukemia|sushi-repeat protein upregulated in leukemia|sushi-repeat-containing protein, X-linked 2
Swissprots O60687 B3KQT3 Q8WW85
Accessions EAX02812 O60687 AF060567 AAC15765 AF393649 AAM73693 AK075462 BAG52145 AU104738 BC020733 AAH20733 BP279501 BU625416 BX339682 DA707631 XM_005262121 XP_005262178 NM_014467 NP_055282
Function Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development. {ECO:0000269|PubMed:16497722, ECO:0000269|PubMed:18718938, ECO:0000269|PubMed:19065654, ECO:0000269|PubMed:24179158}.
Subcellular Location Secreted. Cytoplasm. Cell surface. Cell junction, synapse {ECO:0000250}.
Tissue Specificity Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines and in gastrointestinal cancer cells. Higher levels found in colorectal cancers than in normal colonic mucosa. {ECO:0000269|PubMed:16497722, ECO:0000269|PubMed:18718938, ECO:0000269|PubMed:19065654, ECO:0000269|PubMed:22242148, ECO:0000269|PubMed:9864177}.

SRPX2 - MBS1270932 from MyBioSource

Species Human
Accession BC020733

Human SRPX2 cDNA clone(NM_014467.2) - CDFH018645 from Creative Biomart

Species Human
Accession NM_014467.2

Human SRPX2 ORF Clone(NM_014467.2) - CDCL177053 from Creative Biomart

Species Human
Accession NM_014467.2

human SRPX2 ORF clone - CDCH086002 from Creative Biomart

Species Human
Accession NM_014467

human SRPX2 ORF clone - CDCH086003 from Creative Biomart

Species Human
Accession NM_014467

Human SRPX2 ORF Clone(NM_014467.2) - CDCR297607 from Creative Biomart

Species Human
Accession NM_014467.2

Human SRPX2 ORF Clone(NM_014467.2) - CDCR297608 from Creative Biomart

Species Human
Accession NM_014467.2

Human SRPX2 ORF Clone(NM_014467.2) - CDCR297609 from Creative Biomart

Species Human
Accession NM_014467.2

Human SRPX2 ORF Clone(NM_014467.2) - CDCR297607 from Creative biogene

Species Human

Human SRPX2 ORF Clone (BC020733) - CDCS413655 from Creative biogene

Species Human
Accession O60687

Human SRPX2 ORF clone (BC020733) - CDCB159683 from Creative biogene

Species Human

Human SRPX2 cDNA Clone(NM_014467.2) - CDFH018645 from Creative biogene

Species Human
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