SRPX2

Gene Symbol SRPX2
Entrez Gene 27286
Alt Symbol BPP, CBPS, PMGX, RESDX, SRPUL
Species Human
Gene Type protein-coding
Description sushi-repeat containing protein, X-linked 2
Other Description sushi repeat-containing protein SRPX2|sushi-repeat protein up-regulated in leukemia|sushi-repeat protein upregulated in leukemia|sushi-repeat-containing protein, X-linked 2
Swissprots O60687 B3KQT3 Q8WW85
Accessions EAX02812 O60687 AF060567 AAC15765 AF393649 AAM73693 AK075462 BAG52145 AU104738 BC020733 AAH20733 BP279501 BU625416 BX339682 DA707631 XM_005262121 XP_005262178 NM_014467 NP_055282
Function Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development. {ECO:0000269|PubMed:16497722, ECO:0000269|PubMed:18718938, ECO:0000269|PubMed:19065654, ECO:0000269|PubMed:24179158}.
Subcellular Location Secreted. Cytoplasm. Cell surface. Cell junction, synapse {ECO:0000250}.
Tissue Specificity Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines and in gastrointestinal cancer cells. Higher levels found in colorectal cancers than in normal colonic mucosa. {ECO:0000269|PubMed:16497722, ECO:0000269|PubMed:18718938, ECO:0000269|PubMed:19065654, ECO:0000269|PubMed:22242148, ECO:0000269|PubMed:9864177}.

SRPX2 CRISPR/Cas9 KO Plasmid (h) - sc-409898 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRPX2 HDR Plasmid (h) - sc-409898-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRPX2 Double Nickase Plasmid (h) - sc-409898-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRPX2 Double Nickase Plasmid (h2) - sc-409898-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRPX2 CRISPR Activation Plasmid (h) - sc-409898-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRPX2 CRISPR Activation Plasmid (h2) - sc-409898-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRPX2 Lentiviral Activation Particles (h) - sc-409898-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRPX2 Lentiviral Activation Particles (h2) - sc-409898-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRPX2 siRNA (h) - sc-91299 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SRPX2 shRNA Plasmid (h) - sc-91299-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SRPX2 shRNA (h) Lentiviral Particles - sc-91299-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU136691 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2398 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2398 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02386 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02386

SRPX2 siRNA (Human) - CRH9053 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SRPX2 - MBS8212076 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SRPX2 (NM_014467.2) - SHH418060 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SRPX2(NM_014467.2) - SHL035328 from Creative biogene

Category siRNA
Species Reactivities Human

SRPX2 shRNA Plasmid (Human) - CHH9053 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SRPX2 miRNA 3'UTR clone - MiUTR1H-09913 from Creative biogene

Species Reactivities Human
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