SIRT7

Gene Symbol	SIRT7
Entrez Gene	51547
Alt Symbol	SIR2L7
Species	Human
Gene Type	protein-coding
Description	sirtuin 7
Other Description	NAD-dependent deacetylase sirtuin-7|NAD-dependent protein deacetylase sirtuin-7|SIR2-like protein 7|regulatory protein SIR2 homolog 7|silent mating type information regulation 2, S.cerevisiae, homolog 7|sir2-related protein type 7|sirtuin type 7
Swissprots	B3KSU8 A8K2K0 Q9NUS6 Q3MIK4 Q9NRC8 Q9NSZ6
Accessions	CAL00162 CAL48204 CAN36298 EAW89713 Q9NRC8 AF233395 AAF43431 AK002027 BAA92044 AK094326 BAG52860 AK131437 AK131484 AK290265 BAF82954 AL137626 CAB70848 BC017305 AAH17305 BC101791 AAI01792 BC101793 AAI01794 BQ890203 CD579273 DQ892354 ABM83280 DQ895561 ABM86487 XM_006722284 XP_006722347 XM_011523580 XP_011521882 XM_011523581 XP_011521883 XR_430032 XR_933936 NM_016538 NP_057622
Function	NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at 'Lys-18' (H3K18Ac). In contrast to other histone deacetylases, displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. H3K18Ac is mainly present around the transcription start site of genes and has been linked to activation of nuclear hormone receptors. SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions. Also required to restore the transcription of ribosomal RNA (rRNA) at the exit from mitosis: promotes the association of RNA polymerase I with the rDNA promoter region and coding region. Stimulates transc
Subcellular Location	Cytoplasm. Nucleus, nucleolus. Note=Located close to the nuclear membrane when in the cytoplasm. Associated with chromatin. Associated with rDNA promoter and transcribed region. Associated with nucleolar organizer regions during mitosis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SIRT7 / Sirtuin 7 ELISA Kit (Sandwich ELISA) - LS-F8297 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.31 ng/ml Range 0.781-50 ng/ml

NAD-dependent deacetylase sirtuin-7 (SIRT7/SIR2L7), Human, ELISA Kit - CSB-E17019h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Sirtuin 7 (SIRT7), Human, ELISA Kit - SEE917Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.071ng/mL Range 0.156-10ng/mL

SIRT7 (Human) IP-WB Antibody Pair - H00051547-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) , ELISA Kit - MBS705953 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sirtuin 7, ELISA Kit - MBS096059 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sirtuin 7, ELISA Kit - MBS067938 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sirtuin 7, ELISA Kit - MBS075874 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sirtuin 7, ELISA Kit - MBS050285 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sirtuin 7, ELISA Kit - MBS085639 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sirtuin 7, ELISA Kit - MBS086987 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sirtuin 7, ELISA Kit - MBS055777 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sirtuin 7 (SIRT7), ELISA Kit - MBS2021722 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.31ng/mL. Range 0.781-50ng/mL

ELISA Kit for Sirtuin 7 (SIRT7) - SEE917Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.31ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human NAD-dependent deacetylase sirtuin-7 (SIRT7/SIR2L7) ELISA kit - CSB-E17019h from Cusabio Category ELISA Kit Sensitivity 0.31 ng/ml Range Request Information

ELISA Kit for Sirtuin 7 (SIRT7) - SEE917Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.31ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Rat SIRT7 / Sirtuin 7 ELISA Kit (Custom ELISA) - LS-F16157 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Bovine SIRT7 / Sirtuin 7 ELISA Kit (Custom ELISA) - LS-F16158 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Human SIRT7 / Sirtuin 7 ELISA Kit (Custom ELISA) - LS-F16156 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Mouse SIRT7 / Sirtuin 7 ELISA Kit (Custom ELISA) - LS-F16155 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Human Sirtuin 7 (SIRT7) ELISA Kit - EKU07359 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.27 ng/mL Range 0.78-50 ng/mL

Human NAD-dependent deacetylase sirtuin-7 ELISA Kit - abx250560 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Human Sirtuin 7 ELISA Kit - abx153098 from Abbexa Category ELISA Kit Sensitivity 0.071 ng/ml Range 0.156 ng/ml - 10 ng/ml

Sirtuin 7 (SIRT7), Human, ELISA Kit - DL-SIRT7-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human SIRT7 ELISA Kit - abx571381 from Abbexa Category ELISA Kit Sensitivity 0.071 ng/ml Range 0.156 ng/ml - 10 ng/ml

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