| Gene Symbol |
SRSF6
|
| Entrez Gene |
6431
|
| Alt Symbol |
B52, HEL-S-91, SFRS6, SRP55
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serine/arginine-rich splicing factor 6
|
| Other Description |
SR splicing factor 6|epididymis secretory protein Li 91|pre-mRNA-splicing factor SRP55|splicing factor, arginine/serine-rich, 55 kDa
|
| Swissprots |
Q9UJB8 Q13247 Q13244 Q13245 Q96J06 B7Z6J3 E1P5W6 Q9Y3N7
|
| Accessions |
EAW75964 EAW75965 EAW75966 EAW75967 Q13247 AB208976 BAD92213 AB451251 BAG70065 AB451375 BAG70189 AK123171 AK291203 BAF83892 AK300411 BAH13279 AL110214 AV704620 BC006832 AAH06832 BM788391 BM830876 DC306805 EU668347 ACF94500 U30828 AAA93071 U30883 AAA93073 XR_936608 NM_006275 NP_006266 NR_034009
|
| Function |
Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing. {ECO:0000269|PubMed:12549914, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:22767602, ECO:0000269|PubMed:24440982}.
|
| Subcellular Location |
Nucleus. Nucleus speckle.
|
| Top Pathways |
Spliceosome, Herpes simplex infection
|