SRSF6

Gene Symbol SRSF6
Entrez Gene 6431
Alt Symbol B52, HEL-S-91, SFRS6, SRP55
Species Human
Gene Type protein-coding
Description serine/arginine-rich splicing factor 6
Other Description SR splicing factor 6|epididymis secretory protein Li 91|pre-mRNA-splicing factor SRP55|splicing factor, arginine/serine-rich, 55 kDa
Swissprots Q9UJB8 Q13247 Q13244 Q13245 Q96J06 B7Z6J3 E1P5W6 Q9Y3N7
Accessions EAW75964 EAW75965 EAW75966 EAW75967 Q13247 AB208976 BAD92213 AB451251 BAG70065 AB451375 BAG70189 AK123171 AK291203 BAF83892 AK300411 BAH13279 AL110214 AV704620 BC006832 AAH06832 BM788391 BM830876 DC306805 EU668347 ACF94500 U30828 AAA93071 U30883 AAA93073 XR_936608 NM_006275 NP_006266 NR_034009
Function Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing. {ECO:0000269|PubMed:12549914, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:22767602, ECO:0000269|PubMed:24440982}.
Subcellular Location Nucleus. Nucleus speckle.
Top Pathways Spliceosome, Herpes simplex infection

SRp55 (G-15) - sc-34198 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SRp55 (G-15): sc-34198. Western blot analysis of SRp55 expression in CCRF-CEM (A), human PBL (B) and rat PBL (C) whole cell lysates and HL-60 (D), K-562 (E) and HeLa (F) nuclear extracts.

SRp55 (16H3) - sc-57954 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SRp55 (16H3): sc-57954. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

SRp55 (D-14) - sc-34197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SRp55 (D-14): sc-34197. Western blot analysis of SRp55 expression in CCRF-CEM (A), human PBL (B) and rat PBL (C) whole cell lysates and K-562 nuclear extract (D).

SRp55 (N-15) - sc-34196 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SRp55 (N-15): sc-34196. Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing nuclear staining of respiratory epithelial cells.

SRp55 (H-180) - sc-67100 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SR protein repeat antibody - ab187322 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-SR protein repeat antibody (ab187322) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : HeLa total cell extract

Anti-SR protein repeat antibody [EPR9230] - ab140602 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9230
All lanes : Anti-SR protein repeat antibody [EPR9230] (ab140602) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : Jurkat cell lysateLane 3 : K562 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-SR protein repeat antibody [EPR9231] - ab140623 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9231
All lanes : Anti-SR protein repeat antibody [EPR9231] (ab140623) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : Jurkat cell lysateLane 3 : HeLa cell lysateLysates/proteins at 10 µg per lane.

Anti-SRSF6 / SRP55 Antibody IHC-plus™ - LS-B3092 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SRSF6 / SFRS6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3092 concentration 10 ug/ml.

Anti-SRSF6 / SRP55 Antibody (aa250-300) - LS-C290327 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse SRp55 by Western Blot (h and m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug), Jurkat (J; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-SRp55 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. SRp55 was also immunoprecipitated by rabbit anti-SRp55 antibody BL13266, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

Anti-SRSF6 / SRP55 Antibody (clone 5G6) - LS-C139427 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5G6
Western blot of SFRS6 expression in transfected 293T cell line by SFRS6 monoclonal antibody (M02), clone 5G6.

Anti-SRSF6 / SRP55 Antibody (aa143-192) IHC-plus™ - LS-B5712 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5712 concentration 5 ug/ml.

SRp55 Antibody - NBP1-90043 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SRp55 Antibody [NBP1-90043] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

SRp55 Antibody - NBP2-04142 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SRp55 Antibody [NBP2-04142] - analysis of SRp55 in human lymphocytes using anti-SRp55 antibody. Each lane loaded with 14ug of whole cell lysate with 3 different human B-cell lines. Image from verified customer review.

SRp55 Antibody - NBP1-57112 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SRp55 Antibody [NBP1-57112] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

SRp55 Antibody (5G6) - H00006431-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5G6

SRp55 Antibody (6A10) - H00006431-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6A10
Sandwich ELISA: SRp55 Antibody (6A10) [H00006431-M01] - Detection limit for recombinant GST tagged SFRS6 is approximately 1ng/ml as a capture antibody.

SRp55 Antibody - H00006431-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-SRSF6 antibody produced in rabbit - HPA029005 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SFRS6: <B>Cat. No. HPA029005</B>: Immunohistochemical staining of human colon shows strong nuclear positivity in glandular cells.

Monoclonal Anti-SFRS6 antibody produced in mouse - WH0006431M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6A10
<B>Immunoblotting</B><BR/>Monoclonal Anti-SFRS6, <B>Cat. No. WH0006431M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~34.36 kDa using immunogen protein lysate.

Monoclonal Anti-SFRS6, (N-terminal) antibody produced in mouse - SAB1404364 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5G6
<B>Immunoblotting</B><BR/>Monoclonal Anti-SFRS6: <B>Cat. No. SAB1404364</B>: Antibody concentration: 1 μg/mL. Specific band of ~34.4 kDa using immunogen protein lysate.

SFRS6 antibody - middle region (ARP40632_P050) - ARP40632_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SFRS6-Antibody-monoclonal-M01 - AT3847a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6A10
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (33.99 KDa) .

SFRS6 antibody - 70R-20210 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

SFRS6 antibody - 70R-4617 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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