Gene Symbol | SRSF6 |
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Entrez Gene | 6431 |
Alt Symbol | B52, HEL-S-91, SFRS6, SRP55 |
Species | Human |
Gene Type | protein-coding |
Description | serine/arginine-rich splicing factor 6 |
Other Description | SR splicing factor 6|epididymis secretory protein Li 91|pre-mRNA-splicing factor SRP55|splicing factor, arginine/serine-rich, 55 kDa |
Swissprots | Q9UJB8 Q13247 Q13244 Q13245 Q96J06 B7Z6J3 E1P5W6 Q9Y3N7 |
Accessions | EAW75964 EAW75965 EAW75966 EAW75967 Q13247 AB208976 BAD92213 AB451251 BAG70065 AB451375 BAG70189 AK123171 AK291203 BAF83892 AK300411 BAH13279 AL110214 AV704620 BC006832 AAH06832 BM788391 BM830876 DC306805 EU668347 ACF94500 U30828 AAA93071 U30883 AAA93073 XR_936608 NM_006275 NP_006266 NR_034009 |
Function | Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing. {ECO:0000269|PubMed:12549914, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:22767602, ECO:0000269|PubMed:24440982}. |
Subcellular Location | Nucleus. Nucleus speckle. |
Top Pathways | Spliceosome, Herpes simplex infection |
Human SR protein repeat full length protein - ab159499 from Abcam
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Human SR protein repeat protein fragment - ab159500 from Abcam
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SRSF6 / SRP55 Antibody Blocking Peptide - LS-E14865 from LifeSpan Bioscience
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SRp55 Recombinant Protein - H00006431-P01 from Novus Biologicals
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Recombinant Human SRp55 Protein - H00006431-Q01 from Novus Biologicals
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SFRS6 Blocking Peptide - 33R-4356 from Fitzgerald
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SFRS6 - H00006431-P01 from Acris Antibodies
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SFRS6 - H00006431-P01-10 from Acris Antibodies
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SFRS6 - H00006431-P01-25 from Acris Antibodies
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SFRS6 - H00006431-Q01-10 from Acris Antibodies
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SFRS6 - H00006431-Q01-25 from Acris Antibodies
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SFRS6 fusion protein - ag2412 from Proteintech Group
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Recombinant Human Serine/arginine-rich splicing factor 6(SRSF6) - CSB-YP623793HU CSB-EP623793HU CSB-BP623793HU CSB-MP623793HU from Cusabio
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SRp55 Recombinant Protein Antigen - NBP1-90043PEP from Novus Biologicals
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SRSF6 Peptide, Human - M34GP15184H from Creative Peptides
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Serine/arginine-rich splicing factor 6 (SRSF6), Recombinant Protein - MBS1318047 from MyBioSource
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