NMNAT3

Gene Symbol	NMNAT3
Entrez Gene	349565
Alt Symbol	FKSG76, PNAT-3, PNAT3
Species	Human
Gene Type	protein-coding
Description	nicotinamide nucleotide adenylyltransferase 3
Other Description	NMN adenylyltransferase 3|NMN/NaMN adenylyltransferase 3|NaMN adenylyltransferase 3|nicotinamide mononucleotide adenylyltransferase 3|nicotinamide-nucleotide adenylyltransferase 3|nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3|nicotinate-nucleotide adenylyltransferase 3|pyridine nucleotide adenylyltransferase 3
Swissprots	D3DNF2 B3KVR6 D3DNF3 Q96T66 Q8N4G1
Accessions	EAW79022 EAW79023 EAW79024 EAW79025 EAW79026 EAW79027 EAW79028 EAW79029 EAW79030 EAW79031 EAW79032 EAW79033 Q96T66 AA894638 AF345564 AAK52726 AK123208 BAG53878 AK127477 BAG54510 BC034374 AAH34374 BC036218 AAH36218 BX649063 DB454216 DQ890804 ABM81730 DQ893959 ABM84885 XM_006713624 XP_006713687 XM_006713628 XP_006713691 XM_006713629 XP_006713692 XM_011512790 XP_011511092 XM_011512791 XP_011511093 XM_011512792 XP_011511094 XM_011512793 XP_011511095 NM_001200047 NP_001186976 NM_178177 NP_835471
Function	Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury. {ECO:0000269|PubMed:16118205, ECO:0000269|PubMed:17402747}.
Subcellular Location	Mitochondrion {ECO:0000269|PubMed:12574164, ECO:0000269|PubMed:16118205}.
Tissue Specificity	Expressed in lung and spleen with lower levels in placenta and kidney. {ECO:0000269|PubMed:12574164, ECO:0000269|PubMed:16118205}.
Top Pathways	Nicotinate and nicotinamide metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NMNAT-3 (D-10) - sc-390433 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

NMNAT-3 (C-14) - sc-55865 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

NMNAT-3 (H-80) - sc-134936 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

NMNAT-3 (S-13) - sc-55874 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-NMNAT3 antibody - ab116288 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 antibody - ab71904 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-NMNAT3 Antibody (aa150-178, AP) - LS-C238089 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 Antibody (aa150-178, APC) - LS-C238091 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 Antibody (aa150-178, Biotin) - LS-C238092 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 Antibody (N-Terminus) - LS-C146033 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-NMNAT3 Antibody (aa150-178, FITC) - LS-C238093 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 Antibody (aa150-178, PE) - LS-C238094 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 Antibody (aa150-178, Azide-free, HRP) - LS-C248932 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 Antibody (aa206-220) - LS-C154858 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-NMNAT3 Antibody (aa149-178) - LS-C323380 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 Antibody (aa149-162) - LS-C154857 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-NMNAT3 Antibody (aa149-178) - LS-C162918 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 Antibody (aa236-248) - LS-C87261 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Goat Clonality Polyclonal

NMNAT3 Antibody - NBP2-31675 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

NMNAT3 Antibody - NBP2-27543 from Novus Biologicals Prices $299.00 Sizes 100 µg Host Goat Clonality Polyclonal

NMNAT3 Antibody - H00349565-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

NMNAT3 Antibody - H00349565-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

NMNAT3 Antibody - NB100-93455 from Novus Biologicals Prices $229.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-NMNAT3 antibody produced in rabbit - SAB2106838 from Sigma-Aldrich Prices $341.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-NMNAT3 antibody produced in rabbit - HPA057402 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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