NUP50

Gene Symbol	NUP50
Entrez Gene	10762
Alt Symbol	NPAP60, NPAP60L
Species	Human
Gene Type	protein-coding
Description	nucleoporin 50kDa
Other Description	50 kDa nucleoporin|nuclear pore complex protein Nup50|nuclear pore-associated protein 60L|nucleoporin 50kD|nucleoporin Nup50
Swissprots	Q9NPM9 Q9UKX7 O75644 Q9P1K5 Q9NPR6 Q8N6V5 B2RB15 B1AHA4
Accessions	EAW73370 EAW73372 EAW73373 Q9UKX7 AF107840 AAD53401 AF116624 AAF71047 AF267865 AAG44734 AK095860 AK304223 BAG65095 AK314454 BAG37062 AL389949 CAB97527 AL389950 CAB97528 AL389951 CAB97529 AL704529 BC016055 AAH16055 BC020260 BC028125 AAH28125 BC039468 BC070133 AAH70133 BI461522 CR456533 CAG30419 CU013133 CAK54564 CU013421 CAK54863 EU832782 ACE87793 GQ129293 ACT64427 XM_005261312 XP_005261369 XM_005261313 XP_005261370 XM_005261314 XP_005261371 XM_006724103 XP_006724166 XM_006724104 XP_006724167 XM_011529833 XP_011528135 NM_007172 NP_009103 NM_153645 NP_705931
Function	Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin- alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B. {ECO:0000269|PubMed:20016008}.
Subcellular Location	Nucleus, nuclear pore complex {ECO:0000269|PubMed:12802065}. Nucleus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Nucleoplasmic side {ECO:0000250}. Note=Localizes to the nucleoplasmic fibrils of the nuclear pore complex (By similarity). Dissociates from the NPC structure early during prophase of mitosis. Associates to the newly formed nuclear membrane during telophase. {ECO:0000250}.
Tissue Specificity	Ubiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NUP50 full length protein - ab132507 from Abcam Category Protein Source Wheat germ Species Human

Human NUP50 peptide - ab22982 from Abcam Category Peptide Species Human

Human NUP50 protein fragment - ab161143 from Abcam Category Protein Source Wheat germ Species Human

NUP50 Antibody Blocking Peptide - LS-E4416 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUP50 Antibody Blocking Peptide - LS-E6402 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUP50 Antibody Blocking Peptide - LS-E25524 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUP50 Antibody Blocking Peptide - LS-E18793 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUP50 Antibody Blocking Peptide - LS-E18792 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUP50 Recombinant Protein - H00010762-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NUP50 Protein - H00010762-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NUP50 Peptide - P0661 from Novus Biologicals Category Peptide Species Human

NUP50-Antibody-Center-Blocking-Peptide - BP16725c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NUP50-Antibody-C-term-Blocking-Peptide - BP1913b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Npap60/Nup50 blocking peptide - GTX89862-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

NUP50 Blocking Peptide - 33R-9330 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NUP50 Peptide - AC21-0353-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NUP50 - H00010762-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NUP50 - H00010762-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NUP50 - H00010762-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NUP50 - H00010762-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Nup50 Peptide - 45-985P from ProSci Category Peptide Species Human

NUP50 fusion protein - Ag14710 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NUP50 fusion protein - ag14760 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NUP50 fusion protein - Ag15144 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human NUP50, GST-tagged - NUP50-1418H from Creative Biomart Category Protein Source E.coli Species Human

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