Gene Symbol | UCP1 |
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Entrez Gene | 7350 |
Alt Symbol | SLC25A7, UCP |
Species | Human |
Gene Type | protein-coding |
Description | uncoupling protein 1 (mitochondrial, proton carrier) |
Other Description | mitochondrial brown fat uncoupling protein 1|solute carrier family 25 member 7|thermogenin |
Swissprots | Q13218 Q68G66 Q4KMZ3 P25874 |
Accessions | AAY41026 CAA36214 EAX05095 P25874 BC069556 AAH69556 BC096736 AAH96736 BC098168 AAH98168 BC098258 AAH98258 BC098352 AAH98352 U28480 AAA85271 XM_005263206 XP_005263263 XM_011532228 XP_011530530 NM_021833 NP_068605 |
Function | UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. |
Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. |
Tissue Specificity | Brown adipose tissue. {ECO:0000269|PubMed:3165741}. |
Top Pathways | Huntington's disease, PPAR signaling pathway |
Human UCP1 peptide - ab24282 from Abcam
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Human UCP1 peptide - ab48042 from Abcam
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Human UCP1 protein fragment - ab152782 from Abcam
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UCP1 / UCP-1 Antibody Blocking Peptide - LS-E25984 from LifeSpan Bioscience
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UCP1 / UCP-1 Antibody Blocking Peptide - LS-E23063 from LifeSpan Bioscience
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UCP1 / UCP-1 Antibody Blocking Peptide - LS-E23064 from LifeSpan Bioscience
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Recombinant Human UCP1 Protein - H00007350-Q01 from Novus Biologicals
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UCP1 blocking peptide - GTX89371-PEP from GeneTex
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Human UCP1 protein - orb244618 from Biorbyt
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Human UCP1 protein - orb246029 from Biorbyt
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UCP1 Peptide - AC21-0812-P from Abcore
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SLC25A7 / UCP1 - H00007350-Q01-10 from Acris Antibodies
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SLC25A7 / UCP1 - H00007350-Q01-25 from Acris Antibodies
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UCP1 Peptide - 7697P from ProSci
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UCP1 Peptide - 46-548P from ProSci
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UCP1 fusion protein - ag16153 from Proteintech Group
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UCP1 fusion protein - ag20389 from Proteintech Group
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UCP1 fusion protein - Ag20388 from Proteintech Group
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UCP1 fusion protein - Ag16739 from Proteintech Group
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Recombinant Human UCP1, His-tagged - UCP1-9176H from Creative Biomart
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Recombinant Uncoupling Protein 1, Mitochondrial (UCP1) - RPF557Hu01 from Uscn Life Science Inc.
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Recombinant Uncoupling Protein 1, Mitochondrial (UCP1) - RPF557Mu01 from Uscn Life Science Inc.
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Recombinant Uncoupling Protein 1, Mitochondrial (UCP1) - RPF557Mu02 from Uscn Life Science Inc.
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Recombinant Uncoupling Protein 1, Mitochondrial (UCP1) - RPF557Ra01 from Uscn Life Science Inc.
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Recombinant Uncoupling Protein 1, Mitochondrial (UCP1) - RPF557Ra02 from Uscn Life Science Inc.
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