UCP1

Gene Symbol UCP1
Entrez Gene 7350
Alt Symbol SLC25A7, UCP
Species Human
Gene Type protein-coding
Description uncoupling protein 1 (mitochondrial, proton carrier)
Other Description mitochondrial brown fat uncoupling protein 1|solute carrier family 25 member 7|thermogenin
Swissprots Q13218 Q68G66 Q4KMZ3 P25874
Accessions AAY41026 CAA36214 EAX05095 P25874 BC069556 AAH69556 BC096736 AAH96736 BC098168 AAH98168 BC098258 AAH98258 BC098352 AAH98352 U28480 AAA85271 XM_005263206 XP_005263263 XM_011532228 XP_011530530 NM_021833 NP_068605
Function UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
Subcellular Location Mitochondrion inner membrane; Multi-pass membrane protein.
Tissue Specificity Brown adipose tissue. {ECO:0000269|PubMed:3165741}.
Top Pathways Huntington's disease, PPAR signaling pathway

UCP1 CRISPR/Cas9 KO Plasmid (h) - sc-400410 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UCP1 HDR Plasmid (h) - sc-400410-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UCP1 Double Nickase Plasmid (h) - sc-400410-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UCP1 Double Nickase Plasmid (h2) - sc-400410-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UCP1 CRISPR Activation Plasmid (h) - sc-400410-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UCP1 CRISPR Activation Plasmid (h2) - sc-400410-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UCP1 Lentiviral Activation Particles (h) - sc-400410-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UCP1 Lentiviral Activation Particles (h2) - sc-400410-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UCP1 siRNA (h) - sc-42680 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UCP1 shRNA Plasmid (h) - sc-42680-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UCP1 shRNA (h) Lentiviral Particles - sc-42680-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UCP1 RNAi - H00007350-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU051021 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2479 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2479 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

UCP1 siRNA (Human) - CRH5025 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UCP1 - MBS8214596 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human UCP1 siRNA - orb265527 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UCP1 shRNA Plasmid (Human) - CHH5025 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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