Gene Symbol | GNRHR |
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Entrez Gene | 2798 |
Alt Symbol | GNRHR1, GRHR, HH7, LHRHR, LRHR |
Species | Human |
Gene Type | protein-coding |
Description | gonadotropin-releasing hormone receptor |
Other Description | gnRH receptor|gnRH-R|gonadotropin-releasing hormone (type 1) receptor 1|leutinizing hormone releasing horomone receptor|leutinizing-releasing hormone receptor|luliberin receptor|type I GnRH receptor |
Swissprots | Q92644 Q14D13 O75793 P30968 |
Accessions | AAA63884 AAA63885 AAB71348 CAB17082 CAI72249 EAX05557 EAX05558 P30968 AY392011 AAR92228 BC113546 AAI13547 HQ258385 ADR83139 L03380 AAA35918 L07949 AAA35917 S60587 AAB26287 S77472 AAB33884 Z81148 CAB03541 NM_000406 NP_000397 NM_001012763 NP_001012781 |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle- stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol- calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Pituitary, ovary, testis, breast and prostate but not in liver and spleen. |
Top Pathways | GnRH signaling pathway, Neuroactive ligand-receptor interaction |
Human-GNRHR-cDNA-Clone - DC09816 from Abgent, a WuXi AppTec company
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Human GnRHR (NP_000397) VersaClone cDNA - RDC0324 from R&D Systems
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Mouse GnRHR (NP_034453) VersaClone cDNA - RDC0415 from R&D Systems
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Rat GnRHR (NP_112300) VersaClone cDNA - RDC0611 from R&D Systems
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GNRHR - MBS1266787 from MyBioSource
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Human GNRHR cDNA clone(NM_000406.2) - CDFH007753 from Creative Biomart
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Human GNRHR cDNA clone(NM_001012763.1) - CDFH007754 from Creative Biomart
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Human GNRHR ORF Clone(NM_000406.2) - CDCR336165 from Creative Biomart
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Human GNRHR ORF Clone(NM_000406.2) - CDCR336166 from Creative Biomart
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Human GNRHR ORF Clone(NM_000406.2) - CDCR336171 from Creative Biomart
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Human GNRHR ORF Clone(NM_001012763.1) - CDCR341136 from Creative Biomart
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Human GNRHR ORF Clone(NM_001012763.1) - CDCR341137 from Creative Biomart
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Human GNRHR ORF Clone(NM_000406.2) - CDCL164985 from Creative Biomart
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Human GNRHR ORF Clone(NM_000406.2) - CDCR336165 from Creative biogene
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Mouse GNRHR ORF clone (NM_001012763.1) - CDCL113285 from Creative biogene
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Human GNRHR ORF Clone (BC113546) - CDCS405644 from Creative biogene
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Human GNRHR cDNA Clone(NM_000406.2) - CDFH007753 from Creative biogene
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Human GNRHR cDNA Clone(NM_001012763.1) - CDFH007754 from Creative biogene
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