Gene Symbol | GNRHR |
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Entrez Gene | 2798 |
Alt Symbol | GNRHR1, GRHR, HH7, LHRHR, LRHR |
Species | Human |
Gene Type | protein-coding |
Description | gonadotropin-releasing hormone receptor |
Other Description | gnRH receptor|gnRH-R|gonadotropin-releasing hormone (type 1) receptor 1|leutinizing hormone releasing horomone receptor|leutinizing-releasing hormone receptor|luliberin receptor|type I GnRH receptor |
Swissprots | Q92644 Q14D13 O75793 P30968 |
Accessions | AAA63884 AAA63885 AAB71348 CAB17082 CAI72249 EAX05557 EAX05558 P30968 AY392011 AAR92228 BC113546 AAI13547 HQ258385 ADR83139 L03380 AAA35918 L07949 AAA35917 S60587 AAB26287 S77472 AAB33884 Z81148 CAB03541 NM_000406 NP_000397 NM_001012763 NP_001012781 |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle- stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol- calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Pituitary, ovary, testis, breast and prostate but not in liver and spleen. |
Top Pathways | GnRH signaling pathway, Neuroactive ligand-receptor interaction |
Human GnRHR peptide - ab94807 from Abcam
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GnRH receptor / GNRHR Antibody Blocking Peptide - LS-E5775 from LifeSpan Bioscience
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GnRH receptor / GNRHR Antibody Blocking Peptide - LS-E26227 from LifeSpan Bioscience
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GnRH receptor / GNRHR Antibody Blocking Peptide - LS-E28489 from LifeSpan Bioscience
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Recombinant Human GnRHR Protein - H00002798-G01-10ug from Novus Biologicals
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GNRHR-Antibody-N-term-Blocking-Peptide - BP18314a from Abgent, a WuXi AppTec company
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GnRHR blocking peptide - GTX89184-PEP from GeneTex
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GNRHR Peptide - AC21-1058-P from Abcore
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GRHR Peptide - 45-708P from ProSci
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GNRHR fusion protein - ag18005 from Proteintech Group
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[Des-Gly10, D-Leu6, ProNHEt9] LH-RH Leuprolide Peptide - 350434 from ABBIOTEC
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Recombinant Gonadotropin Releasing Hormone Receptor (GnRHR) - RPB672Ra01 from Uscn Life Science Inc.
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GNRHR Peptide - abx164758 from Abbexa
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GRHR/LRHR, Peptide - MBS426795 from MyBioSource
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GNRHR Peptide, Human - M34GP06427H from Creative Peptides
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GnRHR Recombinant Protein Antigen - NBP2-55552PEP from Novus Biologicals
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Gonadotropin-releasing hormone receptor (GNRHR), Recombinant Protein - MBS963810 from MyBioSource
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Gonadotropin-releasing hormone receptor (GNRHR), Recombinant Protein - MBS7015921 from MyBioSource
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Gonadotropin-releasing hormone receptor (GNRHR), Recombinant Protein - MBS7015926 from MyBioSource
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Gonadotropin-releasing hormone receptor (GNRHR), Recombinant Protein - MBS7015928 from MyBioSource
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Gonadotropin-releasing hormone receptor (GNRHR), Recombinant Protein - MBS7015932 from MyBioSource
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