Endov

Gene Symbol Endov
Entrez Gene 338371
Alt Symbol A730011L01Rik
Species Mouse
Gene Type protein-coding
Description endonuclease V
Other Description novel endonuclease V protein|putative endonuclease FLJ39025 homolog
Swissprots Q3TCQ4 Q8C9A2 B1ATE4 Q8C3Y1
Accessions EDL34708 EDL34709 EDL34710 Q8C9A2 AK042626 BAC31310 AK084233 AK084548 BAC39216 AK170595 BAE41901 AK172181 BAE42869 AK179832 AK183732 AK209873 BC056486 AAH56486 BY266398 XM_006533589 XP_006533652 XM_011249087 XP_011247389 XR_388482 XR_879709 XR_879710 NM_001164636 NP_001158108 NM_177394 NP_796368
Function Endoribonuclease that specifically cleaves inosine- containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs). Cleaves mRNAs and tRNAs containing inosine. Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'- UIUU-3'. Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing. Binds branched DNA structures (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Nucleus, nucleolus.
Tissue Specificity Highest levels detected in liver with high levels also found in heart, kidney and testis. Expressed at low levels in brain. {ECO:0000269|PubMed:12853604}.

Human Endonuclease V full length protein - ab166165 from Abcam

Category Protein
Source Wheat germ
Species Human
ab166165 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Mouse Endonuclease V(Endov) - CSB-YP806983MO CSB-EP806983MO CSB-BP806983MO CSB-MP806983MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse ENDOV Protein - ENDOV-5199M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

Endonuclease V (Endov), Recombinant Protein - MBS1408621 from MyBioSource

Category Protein
Prices $1,100.00, $1,100.00, $1,330.00, $1,330.00, $1,735.00, $1,735.00, $2,200.00, $2,200.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
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