DNAJC2

Gene Symbol	DNAJC2
Entrez Gene	27000
Alt Symbol	MPHOSPH11, MPP11, ZRF1, ZUO1
Species	Human
Gene Type	protein-coding
Description	DnaJ (Hsp40) homolog, subfamily C, member 2
Other Description	M-phase phosphoprotein 11|dnaJ homolog subfamily C member 2|zuotin related factor 1|zuotin-related factor 1
Swissprots	A4VCI0 Q9BVX1 Q99543
Accessions	EAW83329 EAW83330 Q99543 AI621015 AK126382 AL832847 BC000859 AAH00859 BC012376 BC032854 BC046351 BC056682 BC062703 AAH62703 BC125057 AAI25058 BC139751 AAI39752 BC160045 AAI60045 DA272314 DA691752 X98260 CAA66913 XM_005250269 XP_005250326 XM_011516028 XP_011514330 XM_011516029 XP_011514331 XM_011516030 XP_011514332 NM_001129887 NP_001123359 NM_014377 NP_055192
Function	Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb- repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA sequence 5'-GTCAAGC-3'. {ECO:0000269|PubMed:15802566, ECO:0000269|PubMed:16002468, ECO:0000269|PubMed:21179169}.
Subcellular Location	Nucleus. Cytoplasm, cytosol.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:11034098}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DNAJC2 full length protein - ab132857 from Abcam Category Protein Source Wheat germ Species Human

DNAJC2 / ZRF1 Antibody Blocking Peptide - LS-E21917 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DNAJC2 / ZRF1 Antibody Blocking Peptide - LS-E10372 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DNAJC2 Protein - H00027000-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human DNAJC2 Protein - H00027000-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DNAJC2-Antibody-Center-Blocking-Peptide - BP9885c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DNAJC2 Blocking Peptide - 33R-2481 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ZRF1 - H00027000-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ZRF1 - H00027000-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ZRF1 - H00027000-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ZRF1 - H00027000-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MPP11 fusion protein - Ag2594 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human DNAJC2, His-tagged - DNAJC2-26774TH from Creative Biomart Category Protein Source E. coli

Recombinant Human DnaJ homolog subfamily C member 2(DNAJC2) - CSB-YP858715HU CSB-EP858715HU CSB-BP858715HU CSB-MP858715HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ZRF1 (transcript variant 2) - TP325965 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Zuotin Related Factor 1 (ZRF1) - RPC613Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Zuotin Related Factor 1 (ZRF1) - RPC613Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

DNAJC2 Recombinant Protein Antigen - NBP1-82627PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DNAJC2 Peptide, Human - M34GP04426H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Zuotin Related Factor 1 (ZRF1) - RPU51042 from Biomatik Category Protein Prices $191.00, $331.00, $506.00, $632.96 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

DNAJC2 Recombinant Protein (OPCD00842) - OPCD00842 from Aviva Systems Biology Category Protein Source E.coli Species Human

DnaJ homolog subfamily C member 2 (DNAJC2), Recombinant Protein - MBS1283699 from MyBioSource Category Protein Prices $1,415.00, $1,415.00, $1,645.00, $1,645.00, $2,390.00, $2,390.00, $2,835.00, $2,835.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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