LEFTY1

Gene Symbol LEFTY1
Entrez Gene 10637
Alt Symbol LEFTB, LEFTYB
Species Human
Gene Type protein-coding
Description left-right determination factor 1
Other Description left-right determination factor B|left-right determination, factor B|protein lefty-1|protein lefty-B
Swissprots B2R7U0 Q5TE94 Q53H67 O75610
Accessions AAC33967 EAW69760 O75610 AF081512 AAD48144 AK129605 AK222714 BAD96434 AK309263 AK313115 BAG35937 AY358873 AAQ89232 BC027883 AAH27883 DQ896626 ABM87625 HQ628628 AER93378 NM_020997 NP_066277
Function Required for left-right axis determination as a regulator of LEFTY2 and NODAL.
Subcellular Location Secreted.
Top Pathways TGF-beta signaling pathway

Lefty1 (D7E3G) Rabbit mAb - 12647 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D7E3G
Western blot analysis of extracts from 293 cells, mock transfected (-) or transfected with a construct expressing Myc/DDK-tagged full-length human Lefty1 (hLefty1-Myc/DDK; +), using Lefty1 (D7E3G) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

Lefty1 Antibody - 9620 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Anti-Lefty antibody - ab22569 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab22569 stained mouse embryonic stem cells. The cells were 4% PFA fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab22569, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue).

Anti-Lefty antibody - ab86326 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Lefty antibody (ab86326) at 1 µg/ml + Transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Lefty antibody - ab172487 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Lefty antibody (ab172487) at 1 µg/mlLane 1 : Lefty-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H+L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-Lefty antibody [7C5G1H6H10] - ab34593 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7C5G1H6H10
All lanes : Anti-Lefty antibody [7C5G1H6H10] (ab34593) at 1/2000 dilutionLane 1 : 1µg 6X His tagged unrelated protein (shows that the antibody does not recognize the epitope tag).Lane 2 : 1µg partially purified recombinant 6X his tagged human LeftySecondaryIRDyeTM800 Goat anti-mouse IgG at 1/1000 dilution

Anti-Lefty antibody - C-terminal - ab71268 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Lefty antibody - C-terminal (ab71268) at 1/60 dilution + HL60 cell line lysates at 35 µg

Anti-LEFTYB / LEFTY1 Antibody (aa78-361) - LS-C295107 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant LEFTYB / LEFTY1.

Anti-LEFTYB / LEFTY1 Antibody (aa78-361, Biotin) - LS-C298154 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LEFTYB / LEFTY1 Antibody (aa169-368, Biotin) - LS-C298663 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LEFTYB / LEFTY1 Antibody (aa167-332) - LS-C295109 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant LEFTYB / LEFTY1.

Anti-LEFTYB / LEFTY1 Antibody (aa167-332, Biotin) - LS-C299871 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LEFTYB / LEFTY1 Antibody (aa169-368, Biotin) - LS-C299965 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LEFTYB / LEFTY1 Antibody (aa167-332, FITC) - LS-C302031 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LEFTYB / LEFTY1 Antibody (aa169-368, FITC) - LS-C302535 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LEFTYB / LEFTY1 Antibody (aa78-361, FITC) - LS-C302677 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LEFTYB / LEFTY1 Antibody (aa283-314) - LS-C100882 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with LEFTB antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-LEFTYB / LEFTY1 Antibody - LS-C308747 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-LEFTYB / LEFTY1 Antibody (aa169-368, FITC) - LS-C304198 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LEFTYB / LEFTY1 Antibody - LS-C311341 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LEFTYB / LEFTY1 Antibody (aa169-368) - LS-C295111 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant LEFTYB / LEFTY1.

Anti-LEFTYB / LEFTY1 Antibody (Internal) - LS-C100883 from LifeSpan Bioscience

Prices $250.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of anti-LEFTB Pab LS-C100883 in mouse liver tissue lysates (35 ug/lane). LEFTB(arrow) was detected using the purified Pab (1:60 dilution).

Anti-LEFTYB / LEFTY1 Antibody (aa169-368) - LS-C295112 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant LEFTYB / LEFTY1.

Anti-LEFTYB / LEFTY1 Antibody (N-Terminus) IHC-plus™ - LS-B5830 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LEFTY1 / Lefty antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5830 concentration 5 ug/ml.

Lefty Antibody - AF746 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
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