Gene Symbol | LIPH |
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Entrez Gene | 200879 |
Alt Symbol | AH, ARWH2, HYPT7, LAH2, LPDLR, PLA1B, mPA-PLA1 |
Species | Human |
Gene Type | protein-coding |
Description | lipase, member H |
Other Description | LPD lipase-related protein|lipase H|lipase member H|mPA-PLA1 alpha|membrane-associated phosphatidic acid-selective phospholipase A1-alpha|membrane-bound phosphatidic acid-selective phospholipase A1|phospholipase A1 member B |
Swissprots | Q8TEC7 A2IBA7 Q8WWY8 |
Accessions | ABM67096 EAW78218 Q8WWY8 AK074229 BAB85023 AK122651 BAG53642 AK298380 BAG60616 AY036912 AAK63178 AY093498 AAM18803 BC064941 AAH64941 BI965988 EF186228 ABM67094 EF186229 ABM67095 HQ448078 ADQ32559 XM_006713529 XP_006713592 XM_011512530 XP_011510832 XM_011512531 XP_011510833 NM_139248 NP_640341 |
Function | Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). {ECO:0000269|PubMed:12063250, ECO:0000269|PubMed:12963729}. |
Subcellular Location | Secreted. Membrane; Peripheral membrane protein. |
Tissue Specificity | Present in intestine (at protein level). Expressed in colon, prostate, kidney, pancreas, ovary, testis, intestine, lung and pancreas. Expressed at lower level in brain, spleen and heart. In hair, it is prominently expressed in hair follicles, including the stem cell-rich bulge region. {ECO:0000269|PubMed:12063250, ECO:0000269|PubMed:12213196, ECO:0000269|PubMed:12719377, ECO:0000269|PubMed:17095700}. |
LIPH (T-15) - sc-99503 from Santa Cruz Biotechnology
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Anti-LIPH antibody - ab157482 from Abcam
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Anti-LIPH antibody - ab88768 from Abcam
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Anti-LIPH antibody - ab118303 from Abcam
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Anti-LIPH antibody [EP12065] - ab192615 from Abcam
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Anti-LIPH / Lipase Member H Antibody (aa108-273) - LS-C179148 from LifeSpan Bioscience
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Anti-LIPH / Lipase Member H Antibody (aa259-308) - LS-C145661 from LifeSpan Bioscience
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Anti-LIPH / Lipase Member H Antibody - LS-C308761 from LifeSpan Bioscience
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LIPH Antibody - NBP1-79898 from Novus Biologicals
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LIPH Antibody - NBP2-14194 from Novus Biologicals
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LIPH Antibody - H00200879-B01P from Novus Biologicals
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Anti-LIPH antibody produced in mouse - SAB1400841 from Sigma-Aldrich
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Anti-LIPH antibody produced in rabbit - SAB2107647 from Sigma-Aldrich
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LIPH antibody - C-terminal region (ARP61709_P050) - ARP61709_P050 from Aviva Systems Biology
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AHR antibody - GTX22100 from GeneTex
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AHR antibody [RPT1] - GTX22770 from GeneTex
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AHR antibody [RPT9] - GTX22769 from GeneTex
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LIPH antibody - 70R-18284 from Fitzgerald
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Anti -LIPH (Lipase Member H, LIPH, LPD Lipase-related Protein, Membrane-associatedPhosphatidic Acid-selective Phospholipase A1-alpha, mPA-PLA1 alpha, Phospholipase A1Member B, LPDLR, MPAPLA1, PLA1B) - 129117 from USBiological Life Science
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LIPH antibody - orb78418 from Biorbyt
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LIPH antibody - 70R-10356 from Fitzgerald
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LIPH Antibody - abx037008 from Abbexa
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LIPH antibody - 16602-1-AP from Acris Antibodies
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LIPH antibody - H00200879-B01P from Acris Antibodies
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LIPH antibody - 16602-1-AP from Proteintech Group
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