Gene Symbol | LIPH |
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Entrez Gene | 200879 |
Alt Symbol | AH, ARWH2, HYPT7, LAH2, LPDLR, PLA1B, mPA-PLA1 |
Species | Human |
Gene Type | protein-coding |
Description | lipase, member H |
Other Description | LPD lipase-related protein|lipase H|lipase member H|mPA-PLA1 alpha|membrane-associated phosphatidic acid-selective phospholipase A1-alpha|membrane-bound phosphatidic acid-selective phospholipase A1|phospholipase A1 member B |
Swissprots | Q8TEC7 A2IBA7 Q8WWY8 |
Accessions | ABM67096 EAW78218 Q8WWY8 AK074229 BAB85023 AK122651 BAG53642 AK298380 BAG60616 AY036912 AAK63178 AY093498 AAM18803 BC064941 AAH64941 BI965988 EF186228 ABM67094 EF186229 ABM67095 HQ448078 ADQ32559 XM_006713529 XP_006713592 XM_011512530 XP_011510832 XM_011512531 XP_011510833 NM_139248 NP_640341 |
Function | Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). {ECO:0000269|PubMed:12063250, ECO:0000269|PubMed:12963729}. |
Subcellular Location | Secreted. Membrane; Peripheral membrane protein. |
Tissue Specificity | Present in intestine (at protein level). Expressed in colon, prostate, kidney, pancreas, ovary, testis, intestine, lung and pancreas. Expressed at lower level in brain, spleen and heart. In hair, it is prominently expressed in hair follicles, including the stem cell-rich bulge region. {ECO:0000269|PubMed:12063250, ECO:0000269|PubMed:12213196, ECO:0000269|PubMed:12719377, ECO:0000269|PubMed:17095700}. |
Human LIPH full length protein - ab165869 from Abcam
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Human LIPH full length protein - ab165870 from Abcam
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LIPH / Lipase Member H Antibody Blocking Peptide - LS-E22531 from LifeSpan Bioscience
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Recombinant Human LIPH Protein - H00200879-P01 from Novus Biologicals
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Recombinant Human LIPH Protein - H00200879-P02 from Novus Biologicals
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LIPC Recombinant Protein - GTX48178-PRO from GeneTex
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LIPH Blocking Peptide - 33R-10361 from Fitzgerald
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LIPH - H00200879-P01-10 from Acris Antibodies
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LIPH - H00200879-P01-25 from Acris Antibodies
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LIPH - H00200879-P02 from Acris Antibodies
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LIPH fusion protein - Ag9775 from Proteintech Group
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Recombinant Human Lipase member H - BP001349-C663 from Syd Labs
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Recombinant Human LIPH, His-tagged - LIPH-127H from Creative Biomart
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Recombinant Lipase H (LIPH) - RPE175Hu01 from Uscn Life Science Inc.
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Recombinant Lipase H (LIPH) - RPE175Hu01 from Cloud-clone
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Recombinant Human Lipase member H(LIPH) - CSB-YP848833HU CSB-EP848833HU CSB-BP848833HU CSB-MP848833HU from Cusabio
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LIPH fusion protein - Ag24009 from Proteintech Group
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LIPH Recombinant Protein Antigen - NBP2-14194PEP from Novus Biologicals
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LIPH Peptide, Human - M34GP08742H from Creative Peptides
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Lipase member H (LIPH), Recombinant Protein - MBS1399799 from MyBioSource
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