WASL

Gene Symbol	WASL
Entrez Gene	8976
Alt Symbol	N-WASP, NWASP
Species	Human
Gene Type	protein-coding
Description	Wiskott-Aldrich syndrome-like
Other Description	neural Wiskott-Aldrich syndrome protein
Swissprots	A1JUI9 O00401 Q7Z746
Accessions	EAL24333 EAW83599 O00401 AK023554 AK131016 AK289795 BAF82484 AM295156 CAL26602 BC013776 BC028602 BC052955 AAH52955 CB990698 CF593336 CR749438 CAH18276 D88460 BAA20128 DB380642 NM_003941 NP_003932
Function	Regulates actin polymerization by stimulating the actin- nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression. {ECO:0000269\|PubMed:19366662, ECO:0000269\|PubMed:19487689, ECO:0000269\|PubMed:22847007, ECO:0000269\|PubMed:22921828}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}. Note=Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated. {ECO:0000250}.
Top Pathways	Fc gamma R-mediated phagocytosis, Choline metabolism in cancer, Salmonella infection, Bacterial invasion of epithelial cells, Chemokine signaling pathway

N-WASP (30D10) Rabbit mAb - 4848 from Cell Signaling Technology

Prices	$99.00, $246.00
Sizes	20 µl (2 western blots), 100 µl (10 western blots)
Host	Rabbit
Clonality	Monoclonal
Clone	30D10

Western blot analysis of extracts from various cell types, using N-WASP (30D10) Rabbit mAb.

N-WASP (C-1) - sc-271484 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

N-WASP (C-1): sc-271484. Western blot analysis of N-WASP expression in SH-SY5Y whole cell lysate.

N-WASP (H-100) - sc-20770 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

N-WASP (H-100): sc-20770. Western blot analysis of N-WASP expression in SK-N-SH (A) and SH-SY5Y (B) whole cell lysates.

N-WASP (D-15) - sc-10122 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

N-WASP (D-15): sc-10122. Western blot analysis of N-WASP expression in rat brain extract.

N-WASP (N-15) - sc-10121 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

N-WASP (N-15): sc-10121. Western blot analysis of N-WASP expression in SH-SY5Y whole cell lysate.

N-WASP (93-W) - sc-100964 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

N-WASP (93-W): sc-100964. Western blot analysis of N-WASP expression in IMR-32 whole cell lysate.

Anti-N WASP (phospho Y256) antibody - ab23395 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-N WASP (phospho Y256) antibody (ab23395) at 1/10000 dilutionLane 1 : Control A431 cells 20ug/laneLane 2 : Pervanadate-treated A431 cells 20 ug/lane

Anti-N WASP antibody - ab187527 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat spleen tissue labelling N WASP with ab187527 at 1/100. Magnification: 400x.

Anti-N WASP antibody - ab23394 from Abcam

Prices	$378.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-N WASP antibody (ab23394) at 1/1000 dilutionLane 1 : neonatal rat brain lysate control with 5% non fat milk, PBS, 0.04% Tween20Lane 2 : neonatal rat brain lysate alkaline phosphatase treated with 5% non fat milk, PBS, 0.04% Tween20

Anti-N WASP antibody - ab56454 from Abcam

Prices	$378.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-N WASP antibody [EPR6959] - ab126626 from Abcam

Prices	$387.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6959

All lanes : Anti-N WASP antibody [EPR6959] (ab126626) at 1/1000 dilutionLane 1 : NIH 3T3 cell lysateLane 2 : F9 cell lysateLane 3 : L929 cell lysateLane 4 : HeLa cell lysateLane 5 : K562 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP conjugated antibody at 1/2000 dilution

Anti-N WASP antibody - C-terminal - ab166657 from Abcam

Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-N WASP antibody - C-terminal (ab166657) at 1/1000 dilutionLane 1 : Mouse brain total cell extractsLane 2 : Mouse thymus total cell extracts

Anti-WASL / N-WASP Antibody (Internal, clone EPR6959) - LS-C152317 from LifeSpan Bioscience

Prices	$485.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6959

IHC of paraffin-embedded human papillary carcinoma using anti-N-WASP antibody.

Anti-WASL / N-WASP Antibody (clone 5F4) - LS-C133098 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	5F4

Immunoperoxidase of monoclonal antibody to WASL on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 0.8 ug/ml]

Anti-WASL / N-WASP Antibody - LS-C332179 from LifeSpan Bioscience

Prices	$255.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry of paraffin-embedded rat spleen using WASL antibody at dilution of 1:100 (400x lens).

Anti-WASL / N-WASP Antibody (N-Terminus) - LS-C18534 from LifeSpan Bioscience

Prices	$530.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-WASL / N-WASP Antibody (aa21-270) - LS-C40248 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-WASL / N-WASP Antibody - LS-C126474 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-WASL / N-WASP Antibody (phospho-Tyr256) - LS-C18538 from LifeSpan Bioscience

Prices	$530.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-WASL / N-WASP Antibody (N-Terminus) - LS-C191404 from LifeSpan Bioscience

Prices	$530.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-WASL / N-WASP Antibody (C-Terminus) - LS-C191405 from LifeSpan Bioscience

Prices	$530.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-WASL / N-WASP Antibody (Ser484/485) - LS-C191406 from LifeSpan Bioscience

Prices	$530.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-WASL / N-WASP Antibody (Tyr256) - LS-C191408 from LifeSpan Bioscience

Prices	$530.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-WASL / N-WASP Antibody (Ser484/485) - LS-C191407 from LifeSpan Bioscience

Prices	$530.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-WASL / N-WASP Antibody - LS-C341439 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

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