WASL

Gene Symbol WASL
Entrez Gene 8976
Alt Symbol N-WASP, NWASP
Species Human
Gene Type protein-coding
Description Wiskott-Aldrich syndrome-like
Other Description neural Wiskott-Aldrich syndrome protein
Swissprots A1JUI9 O00401 Q7Z746
Accessions EAL24333 EAW83599 O00401 AK023554 AK131016 AK289795 BAF82484 AM295156 CAL26602 BC013776 BC028602 BC052955 AAH52955 CB990698 CF593336 CR749438 CAH18276 D88460 BAA20128 DB380642 NM_003941 NP_003932
Function Regulates actin polymerization by stimulating the actin- nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression. {ECO:0000269|PubMed:19366662, ECO:0000269|PubMed:19487689, ECO:0000269|PubMed:22847007, ECO:0000269|PubMed:22921828}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}. Note=Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated. {ECO:0000250}.
Top Pathways Fc gamma R-mediated phagocytosis, Choline metabolism in cancer, Salmonella infection, Bacterial invasion of epithelial cells, Chemokine signaling pathway

N-WASP CRISPR/Cas9 KO Plasmid (h) - sc-401440 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-WASP HDR Plasmid (h) - sc-401440-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-WASP Double Nickase Plasmid (h) - sc-401440-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-WASP Double Nickase Plasmid (h2) - sc-401440-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-WASP CRISPR Activation Plasmid (h) - sc-401440-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-WASP CRISPR Activation Plasmid (h2) - sc-401440-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-WASP Lentiviral Activation Particles (h) - sc-401440-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-WASP Lentiviral Activation Particles (h2) - sc-401440-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-WASP siRNA (h) - sc-36006 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

N-WASP shRNA Plasmid (h) - sc-36006-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

N-WASP shRNA (h) Lentiviral Particles - sc-36006-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

N-WASP RNAi - H00008976-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU038721 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22784 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22784 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

WASL siRNA (Human) - CRH5926 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

WASL - MBS8234952 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human WASL (NM_003941.2) - SHH445660 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human WASL(NM_003941.2) - SHL129774 from Creative biogene

Category siRNA
Species Reactivities Human

Human WASL siRNA - orb266428 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

WASL shRNA Plasmid (Human) - CHH5926 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

WASL miRNA 3'UTR clone - MiUTR1H-11187 from Creative biogene

Species Reactivities Human
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