Gene Symbol | KAZN |
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Entrez Gene | 23254 |
Alt Symbol | KAZ |
Species | Human |
Gene Type | protein-coding |
Description | kazrin, periplakin interacting protein |
Other Description | kazrin |
Swissprots | Q9UPX4 Q674X6 Q674X7 B1AK78 Q674X4 Q8IYN7 B0QYQ0 Q5TGF1 Q9UIL2 Q6ZUD1 Q8N409 |
Accessions | EAW51704 Q674X7 AB015329 BAA88115 AF052120 AK057155 AK125388 AK293806 BAG57213 AY505119 AAS86434 AY505120 AAS86435 AY505121 AAS86436 AY505122 AAS86437 BC035501 AAH35501 BC101637 AAI01638 BC113621 AAI13622 BC143641 AAI43642 BI916330 DA317442 DN831635 DR003677 XM_005245795 XP_005245852 XM_011541074 XP_011539376 XM_011541075 XP_011539377 XM_011541076 XP_011539378 XM_011541077 XP_011539379 XM_011541078 XP_011539380 XM_011541079 XP_011539381 XM_011541080 XP_011539382 XM_011541081 XP_011539383 XM_011541082 XP_011539384 NM_001017999 NP_001017999 NM_001018000 NP_001018000 NM_001018001 NP_001018001 NM_015209 NP_056024 NM_201628 NP_963922 |
Function | Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. {ECO:0000269|PubMed:15337775}. |
Subcellular Location | Isoform 3: Cytoplasm. Cell junction, desmosome. Nucleus. Note=Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures. |
Tissue Specificity | Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level). {ECO:0000269|PubMed:15337775}. |
Kazrin (N-15) - sc-243130 from Santa Cruz Biotechnology
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Kazrin (Q-19) - sc-243131 from Santa Cruz Biotechnology
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Kazrin (S-20) - sc-243132 from Santa Cruz Biotechnology
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Anti-Kazrin antibody - ab74114 from Abcam
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Anti-Kazrin antibody - ab88752 from Abcam
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Anti-Kazrin antibody - C-terminal - ab138641 from Abcam
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Anti-KAZN Antibody (aa711-739) - LS-C159965 from LifeSpan Bioscience
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Anti-KAZN Antibody - LS-C308586 from LifeSpan Bioscience
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Anti-KAZN Antibody (aa711-739, PE) - LS-C260818 from LifeSpan Bioscience
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Anti-KAZN Antibody (aa710-739) - LS-C322359 from LifeSpan Bioscience
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Anti-KAZN Antibody (aa711-739, Azide-free, HRP) - LS-C260817 from LifeSpan Bioscience
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Anti-KAZN Antibody (aa711-739, AP) - LS-C260813 from LifeSpan Bioscience
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Anti-KAZN Antibody (aa711-739, APC) - LS-C260814 from LifeSpan Bioscience
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Anti-KAZN Antibody (aa711-739, FITC) - LS-C260816 from LifeSpan Bioscience
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Anti-KAZN Antibody (aa711-739, Biotin) - LS-C260815 from LifeSpan Bioscience
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Kazrin Antibody - NBP1-92038 from Novus Biologicals
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Kazrin Antibody - H00023254-B01P from Novus Biologicals
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Kazrin Polyclonal Antibody - bs-9707R from Bioss
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Anti-KAZN antibody produced in rabbit - HPA032096 from Sigma-Aldrich
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ANTI-KAZ(C-TERMINAL) antibody produced in rabbit - SAB1305831 from Sigma-Aldrich
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KAZ-Antibody-C-term - AP18786b from Abgent, a WuXi AppTec company
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KAZ Antibody - C-terminal region (OAAB14324) - OAAB14324 from Aviva Systems Biology
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Anti -KAZ (KAZN, KIAA1026, Kazrin, RP1-21O18.1, HRIHFB2003) - 128727 from USBiological Life Science
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Anti -KAZ, CT (KAZN, KAZ, KIAA1026, Kazrin) - 037277 from USBiological Life Science
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Anti -KAZ, CT (KAZN, KAZ, KIAA1026, Kazrin) (AP) - 037277-AP from USBiological Life Science
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