| Gene Symbol |
KAZN
|
| Entrez Gene |
23254
|
| Alt Symbol |
KAZ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kazrin, periplakin interacting protein
|
| Other Description |
kazrin
|
| Swissprots |
Q9UPX4 Q674X6 Q674X7 B1AK78 Q674X4 Q8IYN7 B0QYQ0 Q5TGF1 Q9UIL2 Q6ZUD1 Q8N409
|
| Accessions |
EAW51704 Q674X7 AB015329 BAA88115 AF052120 AK057155 AK125388 AK293806 BAG57213 AY505119 AAS86434 AY505120 AAS86435 AY505121 AAS86436 AY505122 AAS86437 BC035501 AAH35501 BC101637 AAI01638 BC113621 AAI13622 BC143641 AAI43642 BI916330 DA317442 DN831635 DR003677 XM_005245795 XP_005245852 XM_011541074 XP_011539376 XM_011541075 XP_011539377 XM_011541076 XP_011539378 XM_011541077 XP_011539379 XM_011541078 XP_011539380 XM_011541079 XP_011539381 XM_011541080 XP_011539382 XM_011541081 XP_011539383 XM_011541082 XP_011539384 NM_001017999 NP_001017999 NM_001018000 NP_001018000 NM_001018001 NP_001018001 NM_015209 NP_056024 NM_201628 NP_963922
|
| Function |
Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. {ECO:0000269|PubMed:15337775}.
|
| Subcellular Location |
Isoform 3: Cytoplasm. Cell junction, desmosome. Nucleus. Note=Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.
|
| Tissue Specificity |
Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level). {ECO:0000269|PubMed:15337775}.
|