Gene Symbol | KAZN |
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Entrez Gene | 23254 |
Alt Symbol | KAZ |
Species | Human |
Gene Type | protein-coding |
Description | kazrin, periplakin interacting protein |
Other Description | kazrin |
Swissprots | Q9UPX4 Q674X6 Q674X7 B1AK78 Q674X4 Q8IYN7 B0QYQ0 Q5TGF1 Q9UIL2 Q6ZUD1 Q8N409 |
Accessions | EAW51704 Q674X7 AB015329 BAA88115 AF052120 AK057155 AK125388 AK293806 BAG57213 AY505119 AAS86434 AY505120 AAS86435 AY505121 AAS86436 AY505122 AAS86437 BC035501 AAH35501 BC101637 AAI01638 BC113621 AAI13622 BC143641 AAI43642 BI916330 DA317442 DN831635 DR003677 XM_005245795 XP_005245852 XM_011541074 XP_011539376 XM_011541075 XP_011539377 XM_011541076 XP_011539378 XM_011541077 XP_011539379 XM_011541078 XP_011539380 XM_011541079 XP_011539381 XM_011541080 XP_011539382 XM_011541081 XP_011539383 XM_011541082 XP_011539384 NM_001017999 NP_001017999 NM_001018000 NP_001018000 NM_001018001 NP_001018001 NM_015209 NP_056024 NM_201628 NP_963922 |
Function | Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. {ECO:0000269|PubMed:15337775}. |
Subcellular Location | Isoform 3: Cytoplasm. Cell junction, desmosome. Nucleus. Note=Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures. |
Tissue Specificity | Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level). {ECO:0000269|PubMed:15337775}. |
Human Kazrin full length protein - ab161582 from Abcam
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KAZN Antibody Blocking Peptide - LS-E6159 from LifeSpan Bioscience
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Recombinant Human Kazrin Protein - H00023254-P01 from Novus Biologicals
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KAZ-Antibody-C-term-Blocking-Peptide - BP18786b from Abgent, a WuXi AppTec company
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Kazrin - H00023254-P01-10 from Acris Antibodies
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Kazrin - H00023254-P01-25 from Acris Antibodies
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RP1-21O18.1 fusion protein - ag2152 from Proteintech Group
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Recombinant Human Kazrin(KAZN) - CSB-YP731476HU CSB-EP731476HU CSB-BP731476HU CSB-MP731476HU from Cusabio
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RP1-21O18.1 Protein - abx164912 from Abbexa
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Kazrin (transcript variant E) - TP313977 from Acris Antibodies
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Kazrin Recombinant Protein Antigen - NBP1-92038PEP from Novus Biologicals
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Kazrin Recombinant Protein Antigen - NBP2-48622PEP from Novus Biologicals
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KAZN Peptide, Human - M34GP07906H from Creative Peptides
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RP1-21O18.1 Antibody - SH-A15298 from Novatein Biosciences
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Kazrin (KAZN), Recombinant Protein - MBS1404855 from MyBioSource
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Recombinant Human KIAA1026 Protein, MYC/DDK-tagged - KAZN-147H from Creative Biomart
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