Gene Symbol | RAB12 |
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Entrez Gene | 201475 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAB12, member RAS oncogene family |
Other Description | putative Ras-related protein Rab-12|ras-related protein Rab-12 |
Swissprots | Q4KMQ3 A6NEF5 Q6IQ22 |
Accessions | EAX01616 Q6IQ22 AK127824 BC050338 BC071600 AAH71600 BC098407 AAH98407 XM_006722300 XP_006722363 NM_001025300 NP_001020471 |
Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity). {ECO:0000250}. |
Subcellular Location | Recycling endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Lysosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. Cytoplasmic vesicle, autophagosome {ECO:0000250}. |
Rab 12 (K-14) - sc-85109 from Santa Cruz Biotechnology
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Rab 12 (P-17) - sc-85110 from Santa Cruz Biotechnology
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Anti-RAB12 antibody - ab122666 from Abcam
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Anti-RAB12 antibody - ab170046 from Abcam
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Anti-RAB12 Antibody (aa63-92, AP) - LS-C267662 from LifeSpan Bioscience
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Anti-RAB12 Antibody (aa63-92, Biotin) - LS-C267664 from LifeSpan Bioscience
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Anti-RAB12 Antibody (aa63-92, FITC) - LS-C267665 from LifeSpan Bioscience
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Anti-RAB12 Antibody (aa63-92, APC) - LS-C267663 from LifeSpan Bioscience
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Anti-RAB12 Antibody (aa63-92, Azide-free, HRP) - LS-C267666 from LifeSpan Bioscience
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Anti-RAB12 Antibody (aa70-100) - LS-C324459 from LifeSpan Bioscience
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Anti-RAB12 Antibody (aa63-92, PE) - LS-C267667 from LifeSpan Bioscience
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Anti-RAB12 Antibody (aa63-92) - LS-C162359 from LifeSpan Bioscience
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RAB12 Antibody - NBP1-90976 from Novus Biologicals
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Anti-RAB12 antibody produced in rabbit - HPA040727 from Sigma-Aldrich
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ANTI-RAB12 (N-TERM) antibody produced in rabbit - SAB1304097 from Sigma-Aldrich
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RAB12-Antibody-N-term - AP11360a from Abgent, a WuXi AppTec company
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RAB12 Antibody - N-terminal region (OAAB07606) - OAAB07606 from Aviva Systems Biology
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RAB12 Antibody - abx026226 from Abbexa
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RAB12 antibody - 18843-1-AP from Acris Antibodies
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RAB12 (N-term) antibody - AP53537PU-N from Acris Antibodies
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RAB12 antibody - H00201475-B01P from Acris Antibodies
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Rabbit Anti-RAB12 (N-term) - 102-11063 from RayBiotech
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RAB12 antibody (N-term) - STJ41564 from St John's Laboratory Ltd
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RAB12 antibody - 18843-1-AP from Proteintech Group
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Rabbit Anti-Human RAB12 Polyclonal antibody - DPABH-08429 from Creative Diagnostics
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