Gene Symbol | RAB12 |
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Entrez Gene | 201475 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAB12, member RAS oncogene family |
Other Description | putative Ras-related protein Rab-12|ras-related protein Rab-12 |
Swissprots | Q4KMQ3 A6NEF5 Q6IQ22 |
Accessions | EAX01616 Q6IQ22 AK127824 BC050338 BC071600 AAH71600 BC098407 AAH98407 XM_006722300 XP_006722363 NM_001025300 NP_001020471 |
Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity). {ECO:0000250}. |
Subcellular Location | Recycling endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Lysosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. Cytoplasmic vesicle, autophagosome {ECO:0000250}. |
RAB12 Antibody Blocking Peptide - LS-E945 from LifeSpan Bioscience
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RAB12-Antibody-N-term-Blocking-peptide - BP11360a from Abgent, a WuXi AppTec company
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Recombinant Human Ras-related protein Rab-12(RAB12) - CSB-YP753710HU CSB-EP753710HU CSB-BP753710HU CSB-MP753710HU from Cusabio
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RAB12, member RAS oncogene family (RAB12) - TP311472 from Acris Antibodies
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RAB12 Recombinant Protein Antigen - NBP1-90976PEP from Novus Biologicals
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RAB12 Peptide, Human - M34GP12821H from Creative Peptides
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Ras-related protein Rab-12 (RAB12), Recombinant Protein - MBS1344521 from MyBioSource
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Recombinant Human RAB12 Protein, MYC/DDK-tagged - RAB12-218H from Creative Biomart
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