KRT1

Gene Symbol	KRT1
Entrez Gene	3848
Alt Symbol	CK1, EHK, EHK1, EPPK, K1, KRT1A, NEPPK
Species	Human
Gene Type	protein-coding
Description	keratin 1, type II
Other Description	67 kDa cytokeratin|CK-1|cytokeratin 1|cytokeratin-1|epidermolytic hyperkeratosis 1|hair alpha protein|keratin, type II cytoskeletal 1|type-II keratin Kb1
Swissprots	P86104 P85925 P04264 Q14720 Q9H298 Q6GSJ0 B2RA01
Accessions	AAB47721 AAF60327 AAG41947 AFA52002 AFA52003 AFA52004 AFA52005 AFA52006 AFA52007 CBX47449 EAW96642 P04264 AK313986 BAG36698 BC063697 AAH63697 DB112126 M10938 AAA36153 NM_006121 NP_006112
Function	May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. {ECO:0000269|PubMed:17956333, ECO:0000269|PubMed:21544310}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17956333}. Note=Located on plasma membrane of neuroblastoma NMB7 cells.
Tissue Specificity	The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KRT1 Gene cDNA Clone (full-length ORF Clone) - HG16101-G from Sino Biological Species Human Accession NM_006121.3

Human KRT1 natural ORF mammalian expression plasmid, C-His tag - HG16101-CH from Sino Biological Species Human Accession NM_006121.3

Human KRT1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-tagged - HG16101-NF from Sino Biological Species Human Accession NM_006121.3

Human KRT1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-tagged - HG16101-NM from Sino Biological Species Human Accession NM_006121.3

Human KRT1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-tagged - HG16101-NY from Sino Biological Species Human Accession NM_006121.3

Human KRT1 natural ORF mammalian expression plasmid, C-GFPSpark tag - HG16101-ACG from Sino Biological Species Human Accession NM_006121.3

Human KRT1 natural ORF mammalian expression plasmid, C-OFPSpark tag - HG16101-ACR from Sino Biological Species Human Accession NM_006121.3

Human KRT1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG16101-UT from Sino Biological Species Human Accession NM_006121.3

Human KRT1 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-tagged - HG16101-CM from Sino Biological Species Human Accession NM_006121.3

Human KRT1 natural ORF mammalian expression plasmid, C-Flag tag - HG16101-CF from Sino Biological Species Human Accession NM_006121.3

Human KRT1 natural ORF mammalian expression plasmid, N-His tag - HG16101-NH from Sino Biological Species Human Accession NM_006121.3

Human KRT1 natural ORF mammalian expression plasmid, C-HA tag - HG16101-CY from Sino Biological Species Human Accession NM_006121.3

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