Gene Symbol | KRT1 |
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Entrez Gene | 3848 |
Alt Symbol | CK1, EHK, EHK1, EPPK, K1, KRT1A, NEPPK |
Species | Human |
Gene Type | protein-coding |
Description | keratin 1, type II |
Other Description | 67 kDa cytokeratin|CK-1|cytokeratin 1|cytokeratin-1|epidermolytic hyperkeratosis 1|hair alpha protein|keratin, type II cytoskeletal 1|type-II keratin Kb1 |
Swissprots | P86104 P85925 P04264 Q14720 Q9H298 Q6GSJ0 B2RA01 |
Accessions | AAB47721 AAF60327 AAG41947 AFA52002 AFA52003 AFA52004 AFA52005 AFA52006 AFA52007 CBX47449 EAW96642 P04264 AK313986 BAG36698 BC063697 AAH63697 DB112126 M10938 AAA36153 NM_006121 NP_006112 |
Function | May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. {ECO:0000269|PubMed:17956333, ECO:0000269|PubMed:21544310}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:17956333}. Note=Located on plasma membrane of neuroblastoma NMB7 cells. |
Tissue Specificity | The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis. |
Human Cytokeratin 1 protein fragment - ab114282 from Abcam
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KRT1 / CK1 / Cytokeratin 1 Blocking Peptide - LS-E10264 from LifeSpan Bioscience
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KRT1 / CK1 / Cytokeratin 1 Antibody Blocking Peptide - LS-E15558 from LifeSpan Bioscience
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Recombinant Human Cytokeratin 1 Protein - H00003848-Q01 from Novus Biologicals
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KRT1-Antibody-Center-Blocking-Peptide - BP9695c from Abgent, a WuXi AppTec company
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Cytokeratin 1 Blocking Peptide - 33R-3599 from Fitzgerald
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Human Keratin 1 Protein - abx067601 from Abbexa
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Cytokeratin 1 - H00003848-Q01-10 from Acris Antibodies
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Cytokeratin 1 - H00003848-Q01-25 from Acris Antibodies
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Keratin 1 (KRT1), Human - 20-6721 from ARP American Research Products
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Recombinant Human KRT1 - KRT1-26824TH from Creative Biomart
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Recombinant Keratin 1 (KRT1) - RPA492Hu01 from Uscn Life Science Inc.
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Recombinant Keratin 1 (KRT1) - RPA492Mu01 from Uscn Life Science Inc.
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Recombinant Keratin 1 (KRT1) - RPA492Ra01 from Uscn Life Science Inc.
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Recombinant Keratin 1 (KRT1) - RPA492Ra02 from Uscn Life Science Inc.
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Recombinant Keratin 9 (KRT9) - RPA549Hu01 from Cloud-clone
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Recombinant Pseudotsuga menziesii Unknown protein 18 - CSB-YP311121PWM CSB-EP311121PWM CSB-BP311121PWM CSB-MP311121PWM from Cusabio
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Recombinant Vitis rotundifolia Unknown protein 1 - CSB-YP309223VDQ CSB-EP309223VDQ CSB-BP309223VDQ CSB-MP309223VDQ from Cusabio
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Recombinant Human Keratin, type II cytoskeletal 1(KRT1) - CSB-YP012503HU CSB-EP012503HU CSB-BP012503HU CSB-MP012503HU from Cusabio
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Cytokeratin 1 Protein - NBP1-87956PEP from Novus Biologicals
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Cytokeratin 1 Recombinant Protein Antigen - NBP2-49378PEP from Novus Biologicals
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KRT1 Peptide, Human - M34GP08356H from Creative Peptides
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KRT1 Recombinant Protein (OPCD04728) - OPCD04728 from Aviva Systems Biology
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Keratin 1, Recombinant Protein - MBS2031731 from MyBioSource
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Keratin 1 (KRT1), Recombinant Protein - MBS2010199 from MyBioSource
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