KRT1

Gene Symbol KRT1
Entrez Gene 3848
Alt Symbol CK1, EHK, EHK1, EPPK, K1, KRT1A, NEPPK
Species Human
Gene Type protein-coding
Description keratin 1, type II
Other Description 67 kDa cytokeratin|CK-1|cytokeratin 1|cytokeratin-1|epidermolytic hyperkeratosis 1|hair alpha protein|keratin, type II cytoskeletal 1|type-II keratin Kb1
Swissprots P86104 P85925 P04264 Q14720 Q9H298 Q6GSJ0 B2RA01
Accessions AAB47721 AAF60327 AAG41947 AFA52002 AFA52003 AFA52004 AFA52005 AFA52006 AFA52007 CBX47449 EAW96642 P04264 AK313986 BAG36698 BC063697 AAH63697 DB112126 M10938 AAA36153 NM_006121 NP_006112
Function May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. {ECO:0000269|PubMed:17956333, ECO:0000269|PubMed:21544310}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17956333}. Note=Located on plasma membrane of neuroblastoma NMB7 cells.
Tissue Specificity The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis.

Basic Cytokeratin (AE3) - sc-57004 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Basic Cytokeratin (AE3): sc-57004. Western blot analysis of Basic Cytokeratin expression in MCF7 whole cell lysate.

Cytokeratin 1 (E-12) - sc-376224 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 1 (E-12): sc-376224. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane and cytoskeletal localization.

Cytokeratin 1 (N-20) - sc-17091 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Cytokeratin 1 (N-20): sc-17091. Western blot analysis of Cytokeratin 1 expression in SJRH30 whole cell lysate.

Cytokeratin 1 (4D12B3) - sc-65999 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 1 (4D12B3): sc-65999. Western blot analysis of truncated human recombinant Cytokeratin 1 protein.

Cytokeratin 1/10 (LH1) - sc-53251 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cytokeratin 1/10 (LH1): sc-53251. Western blot analysis of Cytokeratin 1/10 expression in Caco-2 whole cell lysate.

Cytokeratin 1/10 (2Q1048) - sc-70906 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Cytokeratin 1 + 5 + 10+ 14 antibody [34(beta)E12] - ab195381 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone 34(beta)E12
Immunohistochemical analysis of paraffin-embedded Human skin tissue labeling Cytokeratin 1 + 5 + 10+ 14 with ab195381 at a 1/20 dilution.

Anti-Cytokeratin 1 antibody - ab93652 from Abcam

Prices $394.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab14404 staining Cytokeratin 1 in Human LNCaP, prostate cancer cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with formaldehyde and blocked with 1% Donkey serum for 1 hour at 22°C. Samples were incubated with primary antibody (1/100 in 1% Donkey serum in PBST) for 1 hour at 22°C. A DyLight® 594-conjugated Donkey anti-rabbit IgG polyclonal (1/200) was used as the secondary antibody. Red - cytokeratin 1, Green - Golgi marker ST3Gal1, Blue - nucleus (DAPI). See Abreview

Anti-Cytokeratin 1 antibody - ab83664 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Cytokeratin 1 antibody (ab83664) at 1 µg/ml + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Cytokeratin 1 antibody - ab111471 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of Cytokeratin 1 staining in Human normal skin formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab111471, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times

Anti-Cytokeratin 1 antibody - ab140821 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue labelling Cytokeratin 1 with ab140821 at 1/100 dilution.

Anti-Cytokeratin 1 antibody - ab194344 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-Cytokeratin 1 antibody (ab194344) at 1/500 dilution + MES-SA/Dx5 lysate at 50 µgSecondaryGoat Anti-Mouse IgG (H+L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-Cytokeratin 1 antibody [EPR14672] - ab187663 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14672
Anti-Cytokeratin 1 antibody [EPR14672] (ab187663) at 1/50000 dilution + Human skin lysate at 20 µgSecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-Cytokeratin 1 antibody [LHK1] - ab81623 from Abcam

Prices $372.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone LHK1

Anti-Cytokeratin 1 antibody [LL017] - ab18389 from Abcam

Prices $372.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone LL017

Anti-Cytokeratin 1 antibody - N-terminal - ab192684 from Abcam

Prices $370.00
Sizes 50 µl
Clonality Polyclonal

Anti-Cytokeratin antibody [34BE12] - ab191208 from Abcam

Prices $378.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone 34BE12
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human prostate tissue labeling Cytokeratin with ab191208 at 1 µg/ml.

Anti-Cytokeratin antibody [AE-3] - ab74650 from Abcam

Prices $385.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone AE-3
ab74650 staining Cytokeratin in goat lung tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 10% BSA for 10 minutes at 21°C; antigen retrieval was by heat mediation in citric acid. Samples were incubated with primary antibody (1/250 in TBS/BSA/azide) for 2 hours at 21°C. A Biotin-conjugated goat anti-mouse IgG polyclonal (1/200) was used as the secondary antibody.Submitted composite image shows positivity in simple lining epithelia of the pleura and alveoli (upper image) and all bronchial and glandular epithelia (lower image).See Abreview

Anti-Cytokeratin antibody [CK-cocktail] - ab115959 from Abcam

Prices $370.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone CK-cocktail

Anti-Cytokeratin antibody [MNF116] - ab756 from Abcam

Prices $378.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone MNF116
Formalin fixed paraffin embedded human lung carcinoma stained with Cytokeratin using ABC and AEC chromogen.

Anti-Cytokeratin antibody [MNF116], prediluted - ab82612 from Abcam

Prices $384.00
Sizes 6 ml
Host Mouse
Clonality Monoclonal
Clone MNF116
ab82612 staining Cytokeratin in human tonsil tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

Anti-pan Keratin antibody - ab190625 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-pan Keratin antibody (ab190625) at 1/500 dilution + extracts from Jurkat cells at 30 µg

Anti-pan Keratin antibody [80] - ab8068 from Abcam

Prices $400.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone 80
ab8068 staining human foreskin tissue sections by Immunohistochemistry (Formalin/PFA-fixed paraffin embedded). Tissue underwent fixation in paraformaldehyde, heat mediated antigen retrieval in 10mM Citrate buffer pH 6.0 in boiling water bath for 10 minutes, followed by cooling at room temperature for 30 minutes. The blocking was done using 1%BSA/5% normal donkey serum in PBS pH 7.4 for 2 hours at room temperature. The primary antibody, diluted 1/10 (PBS pH 7.4, 1%BSA, 0.1% sodium azide) and incubated with sample for 16 hours at 4°C. A HRP-conjugated donkey polyclonal to mouse Ig, diluted 1/1000 was used as the secondary.See Abreview

Anti-Acidic Cytokeratin AE1 Antibody (clone AE1) - LS-C84872 from LifeSpan Bioscience

Prices $560.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone AE1

Anti-KRT1 / CK1 / Cytokeratin 1 Antibody (clone LHK1, DY550) - LS-C180221 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone LHK1
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