GAR1

Gene Symbol GAR1
Entrez Gene 54433
Alt Symbol NOLA1
Species Human
Gene Type protein-coding
Description GAR1 ribonucleoprotein
Other Description GAR1 ribonucleoprotein homolog|H/ACA ribonucleoprotein complex subunit 1|nucleolar protein family A member 1|nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)|snoRNP protein GAR1
Swissprots Q5MJQ2 Q9NY12
Accessions EAX06253 EAX06254 Q9NY12 AA311919 AJ276003 CAB76563 AK310489 AY780787 AAV98357 BC003413 AAH03413 CN428426 DQ894157 ABM85083 EU176271 ABW03722 NM_018983 NP_061856 NM_032993 NP_127460
Function Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. {ECO:0000269|PubMed:10757788, ECO:0000269|PubMed:15044956}.
Subcellular Location Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies).
Top Pathways Ribosome biogenesis in eukaryotes

GAR1 CRISPR/Cas9 KO Plasmid (h) - sc-408237 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAR1 HDR Plasmid (h) - sc-408237-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAR1 Double Nickase Plasmid (h) - sc-408237-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAR1 Double Nickase Plasmid (h2) - sc-408237-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAR1 CRISPR Activation Plasmid (h) - sc-408237-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAR1 CRISPR Activation Plasmid (h2) - sc-408237-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAR1 Lentiviral Activation Particles (h) - sc-408237-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAR1 Lentiviral Activation Particles (h2) - sc-408237-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAR1 siRNA (h) - sc-38256 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GAR1 shRNA Plasmid (h) - sc-38256-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GAR1 shRNA (h) Lentiviral Particles - sc-38256-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU119761 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9132 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9132 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02959 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02959

GAR1 siRNA (Human) - CRJ0053 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GAR1 - MBS8210631 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GAR1 (NM_018983.3) - SHH299345 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NOLA1(NM_018983.3) - SHH217969 from Creative biogene

Category siRNA
Species Reactivities Human

Human GAR1 siRNA - orb270554 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GAR1 shRNA Plasmid (Human) - CHJ0053 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GAR1 miRNA 3'UTR clone - MiUTR1H-06839 from Creative biogene

Species Reactivities Human

GAR1 miRNA 3'UTR clone - MiUTR3H-08481 from Creative biogene

Species Reactivities Human
Search more