GAR1

Gene Symbol GAR1
Entrez Gene 54433
Alt Symbol NOLA1
Species Human
Gene Type protein-coding
Description GAR1 ribonucleoprotein
Other Description GAR1 ribonucleoprotein homolog|H/ACA ribonucleoprotein complex subunit 1|nucleolar protein family A member 1|nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)|snoRNP protein GAR1
Swissprots Q5MJQ2 Q9NY12
Accessions EAX06253 EAX06254 Q9NY12 AA311919 AJ276003 CAB76563 AK310489 AY780787 AAV98357 BC003413 AAH03413 CN428426 DQ894157 ABM85083 EU176271 ABW03722 NM_018983 NP_061856 NM_032993 NP_127460
Function Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. {ECO:0000269|PubMed:10757788, ECO:0000269|PubMed:15044956}.
Subcellular Location Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies).
Top Pathways Ribosome biogenesis in eukaryotes

GAR1 (G-15) - sc-26984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-NOLA1 antibody - ab188617 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of Human cell line U-2 OS labeling NOLA1 using ab188617 at 4 ug/mL

Anti-NOLA1 antibody - N-terminal - ab200085 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NOLA1 antibody - N-terminal (ab200085) at 1/1000 dilutionLane 1 : Total cell extracts from mouse brainLane 2 : Total cell extracts from mouse thymusLane 3 : Total cell extracts from Human HeLa

Anti-GAR1 / NOLA1 Antibody (aa85-114, APC) - LS-C214582 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GAR1 / NOLA1 Antibody (aa85-114, Biotin) - LS-C214584 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GAR1 / NOLA1 Antibody (aa85-114, AP) - LS-C214581 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GAR1 / NOLA1 Antibody (aa85-114, FITC) - LS-C214585 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GAR1 / NOLA1 Antibody (aa85-114, PE) - LS-C214586 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GAR1 / NOLA1 Antibody (aa86-114) - LS-C157763 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GAR1 Antibody western blot of K562 cell line lysates (35 ug/lane). The GAR1 antibody detected the GAR1 protein (arrow).

Anti-GAR1 / NOLA1 Antibody (aa85-114) - LS-C329564 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GAR1 / NOLA1 Antibody (aa85-114, Azide-free, HRP) - LS-C214587 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

NOLA1 Antibody - NBP2-31742 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: NOLA1 Antibody [NBP2-31742] - Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus & nucleoli.

NOLA1 Antibody - NB100-75347 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-NOLA1 )

ANTI-GAR1 (CENTER) antibody produced in rabbit - SAB1305924 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GAR1 (Center): <B>Cat. No. SAB1305924</B>: GAR1 Antibody (Center) western blot analysis in K562 cell line lysates (35 μg/lane).

Anti-GAR1 antibody produced in rabbit - HPA059098 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GAR1: <B>Cat. No. HPA059098</B>: Immunohistochemical staining of Human colon shows strong nuclear positivity in glandular, endothelial and ganglion cells.

Anti-NOLA1 antibody produced in chicken - GW21964F from Sigma-Aldrich

Prices $267.50
Sizes 50 µg
Host Chicken
Clonality Polyclonal

GAR1-AntibodyCenter - AP19379c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
GAR1 Antibody (Center)(Cat. #AP19379c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GAR1 antibody detected the GAR1 protein (arrow).

NOLA1 antibody - GTX105588 from GeneTex

Host Rabbit
Clonality Polyclonal

nola1 antibody - zf125076 from GeneTex

Host Rabbit
Clonality Polyclonal

NOLA1 antibody - GTX82198 from GeneTex

Prices $339.00
Sizes 50 μg
Host Chicken
Clonality Polyclonal

GAR1 Antibody - middle region (OAAB14959) - OAAB14959 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

GAR1 antibody - 70R-17424 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

NOLA1 antibody - 11711-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded Skin Cancer using 11711-1-AP(GAR1 Antibody) at Dilution 1:50 (under 10x lens)

NOLA1 antibody - H00054433-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

NOLA1 Antibody - XW-7880 from ProSci

Prices $325.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
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