MICU2

Gene Symbol MICU2
Entrez Gene 221154
Alt Symbol 1110008L20Rik, EFHA1
Species Human
Gene Type protein-coding
Description mitochondrial calcium uptake 2
Other Description EF hand domain family A1|EF hand domain family, member A1|EF-hand domain family, member A1|EF-hand domain-containing family member A1|Smhs2 homolog|calcium uptake protein 2, mitochondrial
Swissprots Q8N0T6 Q8IYU8 Q8NAX8
Accessions EAX08312 EAX08313 Q8IYU8 AK057745 AK091907 BAC03769 BC031089 AAH31089 BC034965 AAH34965 BQ438851 JF432114 ADZ15331 JF432150 ADZ15367 XR_429214 NM_152726 NP_689939
Function Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, respectively. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting Ca(2+), avoiding energy dissipation and cell-death triggering. {ECO:0000269|PubMed:24503055, ECO:0000269|PubMed:24560927}.
Subcellular Location Mitochondrion intermembrane space {ECO:0000269|PubMed:24231807, ECO:0000269|PubMed:24560927}.

EF-HA1 (D-15) - sc-84096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

EF-HA1 (E-20) - sc-84097 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-EFHA1 antibody - ab101465 from Abcam

Prices $387.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-EFHA1 antibody (ab101465) at 1/1000 dilution + U87-MG whole cell lysate at 30 µg

Anti-EFHA1 antibody - ab169228 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-EFHA1 antibody (ab169228) at 1 µg/mlLane 1 : EFHA1 transfected 293T lysateLane 2 : Non-transfected 293T lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-EFHA1 antibody - ab177106 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EFHA1 antibody (ab177106) at 1/1000 dilutionLane 1 : K562 lysateLane 2 : MCF7 lysateLane 3 : U373 lysateLane 4 : Human fetal brain lysateLane 5 : Human fetal kidney lysateLane 6 : Human fetal liver lysate

Anti-MICU2 / EFHA1 Antibody - LS-C307910 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

EFHA1 Antibody - NBP2-16278 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EFHA1 Antibody - NBP1-91864 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: EFHA1 Antibody [NBP1-91864] Staining of human stomach, upper shows cytoplasmic positivity in glandular cells.

EFHA1 Antibody - H00221154-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: EFHA1 Antibody [H00221154-B01] - analysis of EFHA1 expression in transfected 293T cell line by EFHA1 MaxPab polyclonal antibody. Lane 1: EFHA1 transfected lysate (47.74 KDa). Lane 2: Non-transfected lysate.

EFHA1 Antibody - H00221154-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: EFHA1 Antibody [H00221154-B01P] - Analysis of EFHA1 expression in transfected 293T cell line by EFHA1 polyclonal antibody. Lane 1: EFHA1 transfected lysate(47.74 KDa). Lane 2: Non-transfected lysate.

EFHA1 Polyclonal Antibody - bs-9011R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EFHA1 antibody produced in mouse - SAB1402057 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-EFHA1, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1402057</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~47.74 kDa using EFHA1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-EFHA1 antibody produced in rabbit - SAB2701367 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-EFHA1: <B>Cat. No. SAB2701367</B>: Immunofluorescence analysis of methanol-fixed MCF-7, using EFHA1 antibody at 1:200 dilution.

Anti-EFHA1 antibody produced in rabbit - HPA045511 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-EFHA1: <B>Cat. No. HPA045511</B>: Immunohistochemical staining of human stomach, upper shows cytoplasmic positivity in glandular cells.

EFHA1 antibody - GTX118555 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-EFHA1 antibody used in ICC/IF. GTX118555

EFHA1 antibody (FITC) - orb3959 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

EFHA1 antibody - orb1929 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

EFHA1 antibody - 70R-17010 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

EFHA1 Antibody - abx036793 from Abbexa

Host Rabbit
Clonality Polyclonal

EFHA1 antibody - 20859-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of HepG2 cells, using EFHA1 antibody 20859-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

EFHA1 antibody - H00221154-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of EFHA1 expression in transfected 293T cell line (H00221154-T01) by EFHA1 MaxPab polyclonal antibody.Lane 1: EFHA1 tra

EFHA1 antibody - H00221154-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of EFHA1 expression in transfected 293T cell line (H00221154-T02) by EFHA1 MaxPab polyclonal antibody. Lane 1: EFHA1 transfected lysate(47.74 KDa). Lane 2: Non-transfected lysate.

EFHA1 antibody - 20859-1-AP from Proteintech Group

Prices $279.00
Sizes con: 42 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 20859-1-AP(EFHA1 antibody) at dilution of 1:800

EFHA1 Antibody - 40054 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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