Gene Symbol | LRRC26 |
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Entrez Gene | 389816 |
Alt Symbol | CAPC, bA350O14.10 |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat containing 26 |
Other Description | BK channel auxiliary gamma subunit LRRC26|BK channel auxilliary gamma subunit LRRC26|cytokeratin associated protein|cytokeratin-associated protein in cancer|leucine-rich repeat-containing protein 26 |
Swissprots | Q5VSG2 B9EIR7 C3RUL3 Q2I0M4 |
Accessions | Q2I0M4 BC140911 AAI40912 CB160046 DN996987 DQ355157 ABC79623 EU588721 ACO90295 NM_001013653 NP_001013675 |
Function | Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low- voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium. {ECO:0000269|PubMed:20613726, ECO:0000269|PubMed:22547800}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Note=Localizes to the cytoplasm when expressed at high levels. {ECO:0000269|PubMed:15164053}. |
Tissue Specificity | Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines. {ECO:0000269|PubMed:16585525, ECO:0000269|PubMed:19250639}. |
LRRC26 Antibody Blocking Peptide - LS-E4075 from LifeSpan Bioscience
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LRRC26-Antibody-C-term-Blocking-Peptide - BP16312b from Abgent, a WuXi AppTec company
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LRRC26 Blocking Peptide - 33R-5378 from Fitzgerald
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LRRC26 Peptide - 7539P from ProSci
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Recombinant Human LRRC26 - LRRC26-1190H from Creative Biomart
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Recombinant Human Leucine-rich repeat-containing protein 26(LRRC26) - CSB-YP646258HU CSB-EP646258HU CSB-BP646258HU CSB-MP646258HU from Cusabio
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LRRC26 Peptide, Human - M34GP08884H from Creative Peptides
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CAPC / LRRC26 Recombinant Protein Antigen - NBP2-30877PEP from Novus Biologicals
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Recombinant Human 2B4/CD244/SLAMF4 Protein - NBP2-59573 from Novus Biologicals
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Leucine-rich repeat-containing protein 26 (LRRC26), Recombinant Protein - MBS1393388 from MyBioSource
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Recombinant Human 2B4/CD244/SLAMF4 Fc Chimera Protein, CF - 1039-2B from Novus Biologicals
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Recombinant Mouse 2B4/CD244/SLAMF4 Fc Chimera Protein, CF - 3514-2B from Novus Biologicals
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