Gene Symbol | LRRC26 |
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Entrez Gene | 389816 |
Alt Symbol | CAPC, bA350O14.10 |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat containing 26 |
Other Description | BK channel auxiliary gamma subunit LRRC26|BK channel auxilliary gamma subunit LRRC26|cytokeratin associated protein|cytokeratin-associated protein in cancer|leucine-rich repeat-containing protein 26 |
Swissprots | Q5VSG2 B9EIR7 C3RUL3 Q2I0M4 |
Accessions | Q2I0M4 BC140911 AAI40912 CB160046 DN996987 DQ355157 ABC79623 EU588721 ACO90295 NM_001013653 NP_001013675 |
Function | Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low- voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium. {ECO:0000269|PubMed:20613726, ECO:0000269|PubMed:22547800}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Note=Localizes to the cytoplasm when expressed at high levels. {ECO:0000269|PubMed:15164053}. |
Tissue Specificity | Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines. {ECO:0000269|PubMed:16585525, ECO:0000269|PubMed:19250639}. |
LRRC26 (P-12) - sc-132327 from Santa Cruz Biotechnology
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LRRC26 (K-12) - sc-132325 from Santa Cruz Biotechnology
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LRRC26 (V-19) - sc-102015 from Santa Cruz Biotechnology
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Anti-LRRC26 antibody - ab124181 from Abcam
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Anti-LRRC26 antibody - ab105838 from Abcam
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Anti-LRRC26 Antibody (aa289-318, AP) - LS-C237224 from LifeSpan Bioscience
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Anti-LRRC26 Antibody (aa289-318, APC) - LS-C237225 from LifeSpan Bioscience
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Anti-LRRC26 Antibody (aa289-318, Biotin) - LS-C237226 from LifeSpan Bioscience
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Anti-LRRC26 Antibody (aa289-318, FITC) - LS-C237227 from LifeSpan Bioscience
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Anti-LRRC26 Antibody (aa289-318, PE) - LS-C237230 from LifeSpan Bioscience
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Anti-LRRC26 Antibody (aa209-258) - LS-C40489 from LifeSpan Bioscience
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Anti-LRRC26 Antibody (aa289-318, Azide-free, HRP) - LS-C248730 from LifeSpan Bioscience
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Anti-LRRC26 Antibody (aa288-319) - LS-C322723 from LifeSpan Bioscience
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Anti-LRRC26 Antibody (aa289-318) - LS-C165874 from LifeSpan Bioscience
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Anti-LRRC26 Antibody (C-Terminus) - LS-C201150 from LifeSpan Bioscience
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CAPC / LRRC26 Antibody - NBP1-70485 from Novus Biologicals
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CAPC / LRRC26 Antibody - NBP2-30877 from Novus Biologicals
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Anti-LRRC26 antibody produced in rabbit - HPA056312 from Sigma-Aldrich
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Anti-LRRC26 antibody produced in rabbit - SAB3501057 from Sigma-Aldrich
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ANTI-LRRC26 (C-TERM) antibody produced in rabbit - SAB1303944 from Sigma-Aldrich
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LRRC26 antibody - middle region (ARP44660_P050) - ARP44660_P050 from Aviva Systems Biology
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LRRC26-Antibody-C-term - AP16312b from Abgent, a WuXi AppTec company
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LRRC26 antibody, Internal - GTX46663 from GeneTex
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LRRC26 Antibody - C-terminal region (OAAB11722) - OAAB11722 from Aviva Systems Biology
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LRRC26 antibody - 70R-6595 from Fitzgerald
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