BAZ1B

Gene Symbol BAZ1B
Entrez Gene 9031
Alt Symbol WBSCR10, WBSCR9, WSTF
Species Human
Gene Type protein-coding
Description bromodomain adjacent to zinc finger domain, 1B
Other Description hWALp2|transcription factor WSTF|tyrosine-protein kinase BAZ1B|williams syndrome transcription factor|williams-Beuren syndrome chromosomal region 10 protein|williams-Beuren syndrome chromosomal region 9 protein
Swissprots Q86UJ6 Q6P1K4 O95039 B9EGK3 O95277 O95247 D3DXE9 Q9UIG0
Accessions AAD04720 AAP22332 EAW69679 EAW69680 EAW69681 Q9UIG0 AB032253 BAA89210 AF072810 AAC97879 AF084479 AAD08675 AK123274 BC041561 BC050599 BC065029 AAH65029 BC080544 BC136520 AAI36521 BU632531 DA739467 XM_005250683 XP_005250740 NM_032408 NP_115784 NM_023005
Function Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication. {ECO:0000269|PubMed:11980720, ECO:0000269|PubMed:15543136, ECO:0000269|PubMe
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00063, ECO:0000255|PROSITE-ProRule:PRU00475, ECO:0000269|PubMed:11980720, ECO:0000269|PubMed:15543136}. Note=Accumulates in pericentromeric heterochromatin during replication. Targeted to replication foci throughout S phase via its association with PCNA.
Tissue Specificity Ubiquitously expressed with high levels of expression in heart, brain, placenta, skeletal muscle and ovary.

WSTF Antibody - 2152 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from various cell types using WSTF Antibody.

WSTF (G-5) - sc-514287 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WSTF (G-5): sc-514287. Western blot analysis of WSTF expression in IMR-32 (A), HeLa (B), HT-1080 (C), PC-12 (D) and SH-SY5Y (E) whole cell lysates.

WSTF (Q-15) - sc-10636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WSTF (Q-15): sc-10636. Western blot analysis of WSTF expression in IMR-32 whole cell lysate.

WSTF (H-20) - sc-10637 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

WSTF (BAZ1H4H9) - sc-81426 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
VAX2 (VAX2A8F12): sc-81422 Western Blot analysis of VAX2 expression in NIH3T3 whole cell lysate.

Anti-WSTF antibody - ab70263 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placenta tissue labelling WSTF with ab70263 at 1/200 (1µg/ml). Detection: DAB.

Anti-WSTF antibody - ab50850 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-WSTF antibody (ab50850) at 0.5 µg/mlLane 1 : HEK-293T extractLane 2 : MCF7 extractLane 3 : Jurkat extractLane 4 : C2 extractLane 5 : 3T3 extractLane 6 : Mouse brain extractLane 7 : PC12 extractLane 8 : AT3B-1 extractLane 9 : RAT1 extractSecondaryGoat Anti-Rabbit IgG, Peroxidase conjugate

Anti-WSTF antibody - ab95216 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-WSTF antibody - ab50706 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-WSTF antibody [BAZ1H4H9] - ab50987 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone BAZ1H4H9
Anti-WSTF antibody [BAZ1H4H9] (ab50987) at 1/100 dilution + HeLa whole cell lysate at 25 µgSecondaryAnti mouse IgG antibody at 1/2500 dilution

Anti-WSTF antibody [EP1704Y] - ab51256 from Abcam

Prices $391.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1704Y
Anti-WSTF antibody [EP1704Y] (ab51256) at 1/20000 dilution + HeLa cell lysate at 10 µgSecondaryGoat anti-Rabbit HRP labeled. at 1/2000 dilution

Anti-WSTF antibody [EPR1703] - ab109439 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1703
All lanes : Anti-WSTF antibody [EPR1703] (ab109439) at 1/1000 dilutionLane 1 : 293T cell lysatesLane 2 : HeLa cell lysatesLane 3 : HT-1080 cell lysatesLane 4 : PC-12 cell lysatesLane 5 : SH-SY5Y cell lysatesLysates/proteins at 10 µg per lane.

Anti-WSTF antibody - Carboxyterminal end - ab50632 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-WSTF antibody - Carboxyterminal end (ab50632) at 2 µg/mlLanes 2, 4 & 5 : Anti-WSTF antibody - Carboxyterminal end (ab50632) at 1 µg/mlLane 3 : Anti-WSTF antibody - Carboxyterminal end (ab50632) at 0.5 µg/mlLane 1 : Mcf7 cell lysate Lane 2 : Mcf7 cell lysate Lane 3 : Mcf7 cell lysate Lane 4 : Mcf7 cell lysate with non-relevant peptide at 10 µg/mlLane 5 : Mcf7 cell lysate with WSTF immunizing peptide at 10 µg/mlSecondaryGoat Anti-Rabbit IgG, Peroxidase conjugate

Anti-BAZ1B / WSTF Antibody (aa157-186, FITC) - LS-C221523 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAZ1B / WSTF Antibody (aa157-186, PE) - LS-C221524 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAZ1B / WSTF Antibody (aa157-186) - LS-C319784 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAZ1B / WSTF Antibody (C-Terminus) - LS-C110406 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BAZ1B / WSTF antibody LS-C110406 Western blot of 293T cell lysate.

Anti-BAZ1B / WSTF Antibody (Internal, clone EPR1703) - LS-C138602 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1703
Western blot analysis on (A) 293T, (B) HeLa, (C) HT-1080, (D) PC-12, and (E) SH-SY5Y cell lysates using anti-WSTF antibody.

Anti-BAZ1B / WSTF Antibody (aa157-186) - LS-C159167 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BAZ1B Antibody western blot of 293 cell line lysates (35 ug/lane). The BAZ1B antibody detected the BAZ1B protein (arrow).

Anti-BAZ1B / WSTF Antibody (aa1-50) - LS-C286663 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human WSTF by Immunohistochemistry. Sample: FFPE section of human non-small cell lung cancer. Antibody: Affinity purified rabbit anti-WSTF used at a dilution of 1:250.

Anti-BAZ1B / WSTF Antibody (aa1-50) - LS-C287332 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human WSTF by Immunohistochemistry. Sample: FFPE section of human placenta. Antibody: Affinity purified rabbit anti-WSTF used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-BAZ1B / WSTF Antibody (clone BAZ1H4H9) - LS-C184285 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone BAZ1H4H9
Immunofluorescent staining using BAZ1B antibody. Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-BAZ1B antibody.

Anti-BAZ1B / WSTF Antibody (C-Terminus, clone EP1704Y) - LS-C49986 from LifeSpan Bioscience

Prices $490.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1704Y
IHC of paraffin-embedded human lymphoma using anti-WTSF antibody.

Anti-BAZ1B / WSTF Antibody (clone BAZ1H4H9) - LS-C342340 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone BAZ1H4H9
Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-BAZ1B mAb.

Anti-BAZ1B / WSTF Antibody (clone 5E9) IHC-plus™ - LS-B6194 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 5E9
Anti-BAZ1B / WSTF antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6194 concentration 3 ug/ml.
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