Gene Symbol | TIPRL |
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Entrez Gene | 261726 |
Alt Symbol | TIP, TIP41 |
Species | Human |
Gene Type | protein-coding |
Description | TOR signaling pathway regulator |
Other Description | TIP41, TOR signaling pathway regulator-like|TIP41-like protein|putative MAPK-activating protein PM10|type 2A-interacting protein |
Swissprots | Q5HYB2 O75663 B2R8V3 Q8IZ86 |
Accessions | EAW90820 EAW90821 O75663 AB097034 BAC77387 AI167356 AK313520 BAG36300 AL049670 CAB41244 BC009506 AAH09506 BX431957 BX648646 CAI46265 XM_011509405 XP_011507707 NM_001031800 NP_001026970 NM_152902 NP_690866 |
Function | May be a allosteric regulator of serine/threonine- protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. {ECO:0000269|PubMed:17384681}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17944932}. |
Tip41 (B-3) - sc-398145 from Santa Cruz Biotechnology
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Tip41 (G-13) - sc-165701 from Santa Cruz Biotechnology
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Tip41 (H-180) - sc-382346 from Santa Cruz Biotechnology
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Anti-TIPRL antibody - ab70795 from Abcam
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Anti-TIPRL antibody - ab71974 from Abcam
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Anti-TIPRL antibody - ab104251 from Abcam
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Anti-TIPRL antibody - ab118695 from Abcam
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Anti-TIPRL antibody - C-terminal - ab173810 from Abcam
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Anti-TIPRL / TIP Antibody (C-Terminus) - LS-C92844 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa200-250) - LS-C92843 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa189-218, AP) - LS-C241808 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa189-218, APC) - LS-C241809 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa189-218, Biotin) - LS-C241810 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa189-218, FITC) - LS-C241811 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa189-218, PE) - LS-C241813 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa189-218, Azide-free, HRP) - LS-C247068 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa200-250) - LS-C287532 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa188-218) - LS-C325736 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa57-106) - LS-C145675 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (C-Terminus) - LS-C287533 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa189-218) - LS-C157200 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (C-Terminus) - LS-C286677 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (aa257-270) IHC-plus⢠- LS-B9212 from LifeSpan Bioscience
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Anti-TIPRL / TIP Antibody (C-Terminus) - LS-C201765 from LifeSpan Bioscience
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TIPRL Antibody (3D11) - NBP2-02269 from Novus Biologicals
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