| Gene Symbol |
TIPRL
|
| Entrez Gene |
261726
|
| Alt Symbol |
TIP, TIP41
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TOR signaling pathway regulator
|
| Other Description |
TIP41, TOR signaling pathway regulator-like|TIP41-like protein|putative MAPK-activating protein PM10|type 2A-interacting protein
|
| Swissprots |
Q5HYB2 O75663 B2R8V3 Q8IZ86
|
| Accessions |
EAW90820 EAW90821 O75663 AB097034 BAC77387 AI167356 AK313520 BAG36300 AL049670 CAB41244 BC009506 AAH09506 BX431957 BX648646 CAI46265 XM_011509405 XP_011507707 NM_001031800 NP_001026970 NM_152902 NP_690866
|
| Function |
May be a allosteric regulator of serine/threonine- protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. {ECO:0000269|PubMed:17384681}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17944932}.
|