Gene Symbol | TIPRL |
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Entrez Gene | 261726 |
Alt Symbol | TIP, TIP41 |
Species | Human |
Gene Type | protein-coding |
Description | TOR signaling pathway regulator |
Other Description | TIP41, TOR signaling pathway regulator-like|TIP41-like protein|putative MAPK-activating protein PM10|type 2A-interacting protein |
Swissprots | Q5HYB2 O75663 B2R8V3 Q8IZ86 |
Accessions | EAW90820 EAW90821 O75663 AB097034 BAC77387 AI167356 AK313520 BAG36300 AL049670 CAB41244 BC009506 AAH09506 BX431957 BX648646 CAI46265 XM_011509405 XP_011507707 NM_001031800 NP_001026970 NM_152902 NP_690866 |
Function | May be a allosteric regulator of serine/threonine- protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. {ECO:0000269|PubMed:17384681}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17944932}. |
Human TIPRL full length protein - ab166096 from Abcam
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TIPRL / TIP Antibody Blocking Peptide - LS-E5614 from LifeSpan Bioscience
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TIPRL / TIP Antibody Blocking Peptide - LS-E22661 from LifeSpan Bioscience
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TIPRL / TIP Antibody Blocking Peptide - LS-E27258 from LifeSpan Bioscience
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Recombinant Human TIPRL Protein - H00261726-P01 from Novus Biologicals
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TIPRL-Antibody-C-term-Blocking-Peptide - BP18140b from Abgent, a WuXi AppTec company
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TIPRL blocking peptide - GTX88075-PEP from GeneTex
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TIPRL Blocking Peptide - 33R-10346 from Fitzgerald
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TIPRL Peptide - AC21-2078-P from Abcore
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TIP41-like protein (TIPRL) - H00261726-P01-10 from Acris Antibodies
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TIP41-like protein (TIPRL) - H00261726-P01-25 from Acris Antibodies
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TIPRL Peptide - 42-500P from ProSci
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TIPRL fusion protein - Ag8780 from Proteintech Group
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TIPRL fusion protein - Ag8951 from Proteintech Group
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Recombinant Human TIPRL, GST-tagged - TIPRL-3244H from Creative Biomart
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Recombinant Human TIP41-like protein(TIPRL) - CSB-YP023569HU CSB-EP023569HU CSB-BP023569HU CSB-MP023569HU from Cusabio
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TIP41-like protein (TIPRL) (transcript variant 1) - TP323912 from Acris Antibodies
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TIPRL, Peptide - MBS427267 from MyBioSource
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TIPRL Recombinant Protein Antigen - NBP1-85169PEP from Novus Biologicals
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TIPRL Recombinant Protein Antigen - NBP2-55024PEP from Novus Biologicals
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