Gene Symbol | SRSF9 |
---|---|
Entrez Gene | 8683 |
Alt Symbol | SFRS9, SRp30c |
Species | Human |
Gene Type | protein-coding |
Description | serine/arginine-rich splicing factor 9 |
Other Description | SR splicing factor 9|pre-mRNA-splicing factor SRp30C|splicing factor, arginine/serine-rich 9 |
Swissprots | Q52LD1 Q13242 |
Accessions | AAD00626 EAW98194 Q13242 AA845918 AI005398 AK290644 BAF83333 AK294254 BAG57550 AK309778 BC093971 AAH93971 BC093973 AAH93973 BU786332 U30825 AAA93069 NM_003769 NP_003760 |
Function | Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10. {ECO:0000269|PubMed:10196175, ECO:0000269|PubMed:11875052, ECO:0000269|PubMed:12024014, ECO:0000269|PubMed:12604611, ECO:0000269|PubMed:15009090, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:15695522, ECO:0000269|PubMed:7556075}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10196175, ECO:0000269|PubMed:11694584, ECO:0000269|PubMed:12024014, ECO:0000269|PubMed:12604611}. Note=Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells. |
Tissue Specificity | Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle. {ECO:0000269|PubMed:10196175}. |
Top Pathways | Spliceosome, Herpes simplex infection |
SRp30c (P-14) - sc-169427 from Santa Cruz Biotechnology
|
||||||||||
SRp30c (N-13) - sc-169426 from Santa Cruz Biotechnology
|
||||||||||
SRp30c (O-21) - sc-134036 from Santa Cruz Biotechnology
|
||||||||||
Anti-SFRS9 antibody - ab74782 from Abcam
|
||||||||||
Anti-SFRS9 antibody - ab88749 from Abcam
|
||||||||||
Anti-SFRS9 antibody - ab172287 from Abcam
|
||||||||||
Anti-SFRS9 antibody - ab155484 from Abcam
|
||||||||||
Anti-SFRS9 antibody - ab200118 from Abcam
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody (clone 7F2) - LS-C340497 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody (clone 5G7) - LS-C340499 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody (aa137-186) IHC-plus™ - LS-B11480 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody (HRP) - LS-C183345 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody (Biotin) - LS-C183347 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody (FITC) - LS-C183346 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody - LS-C190039 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody (Biotin) - LS-C210963 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody (FITC) - LS-C210964 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody (HRP) - LS-C210965 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody IHC-plus™ - LS-B10645 from LifeSpan Bioscience
|
||||||||||
Anti-SRSF9 / SFRS9 Antibody - LS-C334505 from LifeSpan Bioscience
|
||||||||||
SFRS9 Antibody - NBP1-57465 from Novus Biologicals
|
||||||||||
SFRS9 Antibody - NBP1-31904 from Novus Biologicals
|
||||||||||
SFRS9 Antibody (1G7) - H00008683-M01 from Novus Biologicals
|
||||||||||
SFRS9 Antibody - H00008683-B03 from Novus Biologicals
|
||||||||||
Anti-SFRS9 antibody produced in rabbit - AV40490 from Sigma-Aldrich
|