Gene Symbol | VCAM1 |
---|---|
Entrez Gene | 7412 |
Alt Symbol | CD106, INCAM-100 |
Species | Human |
Gene Type | protein-coding |
Description | vascular cell adhesion molecule 1 |
Other Description | CD106 antigen|vascular cell adhesion protein 1 |
Swissprots | E9PDD1 A8K6R7 P19320 Q6NUP8 B4DKS4 |
Accessions | AAA61270 AAM96190 ADZ72971 AEH21939 AEH21940 AEL21381 AEL30503 EAW72949 EAW72950 P19320 AK223266 BAD96986 AK291732 BAF84421 AK296692 BAG59286 AU121762 BC017276 AAH17276 BC068490 AAH68490 BC085003 AAH85003 BF791565 BF968655 CR749464 CAH18296 DB096825 EU831989 ACE87430 EU832082 ACE86744 M30257 AAA51917 M60335 AAA61269 X53051 CAA37218 NM_001078 NP_001069 NM_001199834 NP_001186763 NM_080682 NP_542413 |
Function | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. |
Top Pathways | Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Malaria, African trypanosomiasis, HTLV-I infection |
VCAM1-Over-expression-Lysate - LY16052a from Abgent, a WuXi AppTec company
|
||||||||
VCAM1 overexpression lysate - LY421491 from Acris Antibodies
|
||||||||
VCAM1 293 Cell Lysate - 409518 from ABBIOTEC
|
||||||||
VCAM-1/CD106 Overexpression Lysate (Denatured) - H00007412-T01 from Novus Biologicals
|
||||||||
VCAM-1/CD106 Overexpression Lysate (Native) - NBP2-08467 from Novus Biologicals
|
||||||||
VCAM-1 (h): 293T Lysate - sc-178116 from Santa Cruz Biotechnology
|
||||||||
VCAM1 Over-expression Lysate Product - GWB-45318B from Genway Biotech
|
||||||||
Human VCAM-1 / CD106 HEK293 Cell Lysate (WB positive control) - 10113-H08HL-300 from Sino Biological
|
||||||||
Human VCAM-1 / CD106 HEK293 Cell Lysate (WB positive control) - 10113-H07HL-300 from Sino Biological
|
||||||||
Human VCAM-1 / CD106 HEK293 Cell Lysate (WB positive control) - 10113-H02HL-300 from Sino Biological
|
||||||||
Human CD106 Human Cells Transfected Lysate (positive control) (denatured) - orb173035 from Biorbyt
|
||||||||
VCAM-1/CD106 Overexpression Lysate (Native) - NBP2-05768 from Novus Biologicals
|
||||||||
Human VCAM1 Human Cells Transfected Lysate (positive control) (denatured) - orb173387 from Biorbyt
|
||||||||
Human VCAM1 Human Cells Transfected Lysate (positive control) (denatured) - orb173034 from Biorbyt
|
||||||||
Panoply™ Human VCAM1 Knockdown Stable Cell Line - CSC-DC017249 from Creative biogene
|