VCAM1

Gene Symbol VCAM1
Entrez Gene 7412
Alt Symbol CD106, INCAM-100
Species Human
Gene Type protein-coding
Description vascular cell adhesion molecule 1
Other Description CD106 antigen|vascular cell adhesion protein 1
Swissprots E9PDD1 A8K6R7 P19320 Q6NUP8 B4DKS4
Accessions AAA61270 AAM96190 ADZ72971 AEH21939 AEH21940 AEL21381 AEL30503 EAW72949 EAW72950 P19320 AK223266 BAD96986 AK291732 BAF84421 AK296692 BAG59286 AU121762 BC017276 AAH17276 BC068490 AAH68490 BC085003 AAH85003 BF791565 BF968655 CR749464 CAH18296 DB096825 EU831989 ACE87430 EU832082 ACE86744 M30257 AAA51917 M60335 AAA61269 X53051 CAA37218 NM_001078 NP_001069 NM_001199834 NP_001186763 NM_080682 NP_542413
Function Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
Top Pathways Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Malaria, African trypanosomiasis, HTLV-I infection

VCAM-1 (E1E8X) Rabbit mAb - 13662 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1E8X
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing Myc/DDK-tagged full-length human VCAM-1 (hVCAM-1-Myc/DDK; +), using VCAM-1 (E1E8X) Rabbit mAb.

VCAM-1 Antibody - 12367 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HUVEC cells, untreated (-) or treated with Human Tumor Necrosis Factor-α (hTNF-α) #8902 (10 ng/ml, 16 hr; +), using VCAM-1 Antibody (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

VCAM-1 (C-19) - sc-1504 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VCAM-1 (C-19): sc-1504. Western blot analysis of VCAM-1 expression in L8 (A) and Sol8 (B) whole cell lysates.

VCAM-1 (M/K-2) - sc-18864 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
VCAM-1 (M/K-2): sc-18864. Western blot analysis of VCAM-1 expression in Sol8 whole cell lysate.

VCAM-1 (H-276) - sc-8304 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VCAM-1 (H-276): sc-8304. Immunoperoxidase staining of formalin fixed, paraffin-embedded human renal cancer tissue showing membrane staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

VCAM-1 (E-10) - sc-13160 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VCAM-1 (E-10) PE: sc-13160 PE. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

VCAM-1 (P3C4) - sc-20070 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of purified human VCAM-1 immunoprecipitated with VCAM-1 (P3C4): sc-20070 and detected with VCAM-1 (H-276): sc-8304.

VCAM-1 (HAE-2z) - sc-13506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VCAM-1 (HAE-2z) PE: sc-13506 PE. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

VCAM-1 (1G11) - sc-18854 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VCAM-1 (1G11) PE: sc-18854 PE. FCM analysis of HUV-EC-C cells. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2855.

VCAM-1 (D-20) - sc-31048 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

VCAM-1 (1.BB.619) - sc-73252 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

VCAM-1 (3H1810) - sc-73253 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

Anti-VCAM1 antibody - ab106777 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-VCAM1 antibody (ab106777) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : Human fetal spleen lysateLane 3 : Human fetal kidney lysateLane 4 : Human fetal heart lysate

Anti-VCAM1 antibody - ab123801 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-VCAM1 antibody (ab123801) at 1/50 dilution + HepG2 cell line lysates at 35 µg

Anti-VCAM1 antibody - ab174762 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-VCAM1 antibody (ab174762) at 1 µg/ml + Human Uterus lysate at 35 µgdeveloped using the ECL technique

Anti-VCAM1 antibody - ab167095 from Abcam

Host Sheep
Clonality Polyclonal

Anti-VCAM1 antibody [1.4C3], prediluted - ab74514 from Abcam

Prices $382.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone 1.4C3
Formalin-fixed, paraffin-embedded human tonsil stained with ab74514 using peroxidase-conjugate and AEC chromogen. Note membrane staining of hematopoietic cells in germinal center.

Anti-VCAM1 antibody [1.G11B1] (Phycoerythrin) - ab82438 from Abcam

Prices $186.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 1.G11B1

Anti-VCAM1 antibody [1G11B1] - ab7219 from Abcam

Prices $372.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1G11B1

Anti-VCAM1 antibody [1G11B1] (Biotin) - ab7224 from Abcam

Prices $373.00
Sizes 25 µg
Host Mouse
Clonality Monoclonal
Clone 1G11B1

Anti-VCAM1 antibody [6G9] - ab98954 from Abcam

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6G9
All lanes : Anti-VCAM1 antibody [6G9] (ab98954) at 1/500 dilutionLane 1 : HUVEC cell lysateLane 2 : EC cell lysate

Anti-VCAM1 antibody [B-K9] - ab47159 from Abcam

Prices $378.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone B-K9
A typical staining pattern with the B-K9 monoclonal antibody of VCAM-1 transfected CHO cell line

Anti-VCAM1 antibody [B-K9] - ab27352 from Abcam

Prices $378.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-K9
A typical staining pattern of ab27352 labelling of VCAM1 in transfected CHO cells.

Anti-VCAM1 antibody (Biotin) - ab107519 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-VCAM1 antibody [EPR5038(2)] - ab174279 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5038(2)
All lanes : Anti-VCAM1 antibody [EPR5038(2)] (ab174279) at 1/1000 dilutionLane 1 : Human fetal kidney lysateLane 2 : HuT-78 lysateLane 3 : NIH3T3 lysateLysates/proteins at 10 µg per lane.
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