VCAM1

Gene Symbol VCAM1
Entrez Gene 7412
Alt Symbol CD106, INCAM-100
Species Human
Gene Type protein-coding
Description vascular cell adhesion molecule 1
Other Description CD106 antigen|vascular cell adhesion protein 1
Swissprots E9PDD1 A8K6R7 P19320 Q6NUP8 B4DKS4
Accessions AAA61270 AAM96190 ADZ72971 AEH21939 AEH21940 AEL21381 AEL30503 EAW72949 EAW72950 P19320 AK223266 BAD96986 AK291732 BAF84421 AK296692 BAG59286 AU121762 BC017276 AAH17276 BC068490 AAH68490 BC085003 AAH85003 BF791565 BF968655 CR749464 CAH18296 DB096825 EU831989 ACE87430 EU832082 ACE86744 M30257 AAA51917 M60335 AAA61269 X53051 CAA37218 NM_001078 NP_001069 NM_001199834 NP_001186763 NM_080682 NP_542413
Function Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
Top Pathways Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Malaria, African trypanosomiasis, HTLV-I infection

VCAM-1 CRISPR/Cas9 KO Plasmid (h) - sc-400135 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VCAM-1 HDR Plasmid (h) - sc-400135-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VCAM-1 Double Nickase Plasmid (h) - sc-400135-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VCAM-1 Double Nickase Plasmid (h2) - sc-400135-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VCAM-1 CRISPR Activation Plasmid (h) - sc-400135-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VCAM-1 CRISPR Activation Plasmid (h2) - sc-400135-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VCAM-1 Lentiviral Activation Particles (h) - sc-400135-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VCAM-1 Lentiviral Activation Particles (h2) - sc-400135-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VCAM-1 siRNA (h) - sc-29519 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VCAM-1 shRNA Plasmid (h) - sc-29519-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VCAM-1 shRNA (h) Lentiviral Particles - sc-29519-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU083751 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22653 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22653 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06504 from Sigma-Aldrich

Category miRNA

VCAM1 siRNA (Human) - CRH5071 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

VCAM1 - MBS8224985 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human VCAM1 (NM_001078.3) - SHH442420 from Creative biogene

Category siRNA
Species Reactivities Human

VCAM1 shRNA Plasmid (Human) - CHH5071 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

VCAM1 miRNA 3'UTR clone - MiUTR3H-02395 from Creative biogene

Species Reactivities Human

VCAM1 miRNA 3'UTR clone - MiUTR3H-02396 from Creative biogene

Species Reactivities Human
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