MIEN1

Gene Symbol MIEN1
Entrez Gene 84299
Alt Symbol C17orf37, C35, ORB3, RDX12, XTP4
Species Human
Gene Type protein-coding
Description migration and invasion enhancer 1
Other Description HBV X-transactivated gene 4 protein|HBV XAg-transactivated protein 4|protein C17orf37
Swissprots Q9BRT3
Accessions CAN37613 CCA65398 EAW60598 EAW60599 Q9BRT3 AA010615 AF490253 AAO85461 AJ308025 AJ308026 AL554581 AY508814 AAR92035 BC006006 AAH06006 BC106016 BX646129 HQ448736 ADQ33214 XM_005257736 XP_005257793 NM_032339 NP_115715
Function Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. {ECO:0000269|PubMed:19503095, ECO:0000269|PubMed:21628459}.
Subcellular Location Cytoplasm, cytosol. Cell membrane; Lipid- anchor; Cytoplasmic side. Note=Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
Tissue Specificity Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level). {ECO:0000269|PubMed:17121940, ECO:0000269|PubMed:19503095}.

C35 (C-16) - sc-69346 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

C35 (N-14) - sc-69347 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-XTP4 antibody - ab14762 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-XTP4 antibody - ab88371 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-XTP4 antibody (ab88371) at 1 µg/mlLane 1 : XTP4 transfected 293T cell lysateLane 2 : Non-transfected lysateLysates/proteins at 25 µg per lane.

Anti-XTP4 antibody [1D4] - ab128138 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D4
Overlay histogram showing T47D cells stained with ab128138 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab128138, 1/100 dilution) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in T47D cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-XTP4 antibody [EPR2678] - ab92499 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2678
Anti-XTP4 antibody [EPR2678] (ab92499) at 1/1000 dilution + SKBR3 cell lysate at 10 µgSecondarygoat anti-rabbit HRP at 1/2000 dilution

Anti-XTP4 / C17orf37 Antibody (clone 1E1) - LS-C173883 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 1D7) - LS-C173862 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 1G2) - LS-C173884 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1G2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 1E4) - LS-C173881 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 4D6) - LS-C173890 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4D6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody - LS-C308998 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-XTP4 / C17orf37 Antibody - LS-C310979 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-XTP4 / C17orf37 Antibody (clone 3D9) - LS-C175086 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3D9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 3H9) - LS-C175087 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 3B5) - LS-C139249 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B5
Western blot of C17orf37 expression in transfected 293T cell line by C17orf37 monoclonal antibody (M02), clone 3B5.

Anti-XTP4 / C17orf37 Antibody (clone 2D4) - LS-C336894 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 1A3) - LS-C336892 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 1D4) - LS-C173891 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D4
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-C17orf37 mouse monoclonal antibody.

Anti-XTP4 / C17orf37 Antibody (clone 3D12) - LS-C175085 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3D12
Anti-C17orf37 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 1E8) - LS-C337702 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E8
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 3D2) - LS-C175088 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3D2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C17orf37 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C17orf37.

Anti-XTP4 / C17orf37 Antibody (clone 4D4) - LS-C336891 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4D4
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-C17orf37 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-XTP4 / C17orf37 Antibody (Internal, clone EPR2678) - LS-C105703 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2678
Western blot analysis on SKBR-3 cell lysate using anti-C35 antibody (LS-C105703).

Anti-XTP4 / C17orf37 Antibody (clone 2D5) - LS-C336895 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D5
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-C17orf37 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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