Gene Symbol | MIEN1 |
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Entrez Gene | 84299 |
Alt Symbol | C17orf37, C35, ORB3, RDX12, XTP4 |
Species | Human |
Gene Type | protein-coding |
Description | migration and invasion enhancer 1 |
Other Description | HBV X-transactivated gene 4 protein|HBV XAg-transactivated protein 4|protein C17orf37 |
Swissprots | Q9BRT3 |
Accessions | CAN37613 CCA65398 EAW60598 EAW60599 Q9BRT3 AA010615 AF490253 AAO85461 AJ308025 AJ308026 AL554581 AY508814 AAR92035 BC006006 AAH06006 BC106016 BX646129 HQ448736 ADQ33214 XM_005257736 XP_005257793 NM_032339 NP_115715 |
Function | Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. {ECO:0000269|PubMed:19503095, ECO:0000269|PubMed:21628459}. |
Subcellular Location | Cytoplasm, cytosol. Cell membrane; Lipid- anchor; Cytoplasmic side. Note=Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions. |
Tissue Specificity | Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level). {ECO:0000269|PubMed:17121940, ECO:0000269|PubMed:19503095}. |
Human XTP4 full length protein - ab153550 from Abcam
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Human XTP4 full length protein - ab168086 from Abcam
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XTP4 Recombinant Protein - H00084299-P01 from Novus Biologicals
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Recombinant Human XTP4 Protein - NBP2-23236 from Novus Biologicals
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Human MIEN1 protein - orb191290 from Biorbyt
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MIEN1 protein (His tag) - 80R-2977 from Fitzgerald
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C17orf37 (1-112, His-tag) - AR51095PU-N from Acris Antibodies
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C17orf37 (1-112, His-tag) - AR51095PU-S from Acris Antibodies
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C17orf37 - H00084299-P01-10 from Acris Antibodies
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C17orf37 - H00084299-P01-25 from Acris Antibodies
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C17orf37 - H00125476-P01-25 from Acris Antibodies
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C17orf37 - H00126299-P01-10 from Acris Antibodies
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C17orf37 - H00126299-P01-25 from Acris Antibodies
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MIEN1, 1-112aa, Human, His tag, E.coli - 01-P2271 from ARP American Research Products
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C17orf37 fusion protein - Ag14975 from Proteintech Group
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C17orf37 fusion protein - Ag15084 from Proteintech Group
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Recombinant Human C17orf37, GST-tagged - C17orf37-10416H from Creative Biomart
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Recombinant Human MIEN1, His-tagged - MIEN1-15915H from Creative Biomart
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C35 Blocking Peptide - CBP4087 from Cohesion Biosciences
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Recombinant Human Migration and invasion enhancer 1(MIEN1) - CSB-YP874795HU CSB-EP874795HU CSB-BP874795HU CSB-MP874795HU from Cusabio
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MIEN1, 1-112aa, Human, His tag, E.coli - ATGP2271 from ATGen
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Migration And Invasion Enhancer 1 Protein (Recombinant) - abx261146 from Abbexa
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C17orf37 - TP303346 from Acris Antibodies
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XTP4 Protein - NBP2-33796PEP from Novus Biologicals
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XTP4 Protein - NBP2-34142PEP from Novus Biologicals
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