MIEN1

Gene Symbol MIEN1
Entrez Gene 84299
Alt Symbol C17orf37, C35, ORB3, RDX12, XTP4
Species Human
Gene Type protein-coding
Description migration and invasion enhancer 1
Other Description HBV X-transactivated gene 4 protein|HBV XAg-transactivated protein 4|protein C17orf37
Swissprots Q9BRT3
Accessions CAN37613 CCA65398 EAW60598 EAW60599 Q9BRT3 AA010615 AF490253 AAO85461 AJ308025 AJ308026 AL554581 AY508814 AAR92035 BC006006 AAH06006 BC106016 BX646129 HQ448736 ADQ33214 XM_005257736 XP_005257793 NM_032339 NP_115715
Function Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. {ECO:0000269|PubMed:19503095, ECO:0000269|PubMed:21628459}.
Subcellular Location Cytoplasm, cytosol. Cell membrane; Lipid- anchor; Cytoplasmic side. Note=Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
Tissue Specificity Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level). {ECO:0000269|PubMed:17121940, ECO:0000269|PubMed:19503095}.

C35 CRISPR/Cas9 KO Plasmid (h) - sc-410626 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C35 HDR Plasmid (h) - sc-410626-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C35 Double Nickase Plasmid (h) - sc-410626-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C35 Double Nickase Plasmid (h2) - sc-410626-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C35 CRISPR Activation Plasmid (h) - sc-410626-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C35 CRISPR Activation Plasmid (h2) - sc-410626-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C35 Lentiviral Activation Particles (h) - sc-410626-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C35 Lentiviral Activation Particles (h2) - sc-410626-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C35 siRNA (h) - sc-72767 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C35 shRNA Plasmid (h) - sc-72767-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C35 shRNA (h) Lentiviral Particles - sc-72767-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU021641 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4451 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4451 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03089 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03089

MIEN1 siRNA (Human) - CRJ3422 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C17orf37 (NM_032339.3) - SHH249822 from Creative biogene

Category siRNA
Species Reactivities Human

Human MIEN1 siRNA - orb273923 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MIEN1 shRNA Plasmid (Human) - CHJ3422 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MIEN1 miRNA 3'UTR clone - MiUTR1H-01161 from Creative biogene

Species Reactivities Human
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