MIEN1

Gene Symbol MIEN1
Entrez Gene 84299
Alt Symbol C17orf37, C35, ORB3, RDX12, XTP4
Species Human
Gene Type protein-coding
Description migration and invasion enhancer 1
Other Description HBV X-transactivated gene 4 protein|HBV XAg-transactivated protein 4|protein C17orf37
Swissprots Q9BRT3
Accessions CAN37613 CCA65398 EAW60598 EAW60599 Q9BRT3 AA010615 AF490253 AAO85461 AJ308025 AJ308026 AL554581 AY508814 AAR92035 BC006006 AAH06006 BC106016 BX646129 HQ448736 ADQ33214 XM_005257736 XP_005257793 NM_032339 NP_115715
Function Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. {ECO:0000269|PubMed:19503095, ECO:0000269|PubMed:21628459}.
Subcellular Location Cytoplasm, cytosol. Cell membrane; Lipid- anchor; Cytoplasmic side. Note=Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
Tissue Specificity Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level). {ECO:0000269|PubMed:17121940, ECO:0000269|PubMed:19503095}.

C17orf37-Over-expression-Lysate - LY13517a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag C17orf37 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the C17orf37 gene

C17orf37 293T Cell Transient Overexpression Lysate(Denatured) - H00084299-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

C17orf37 293 Cell Lysate - 405234 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

XTP4 Overexpression Lysate (Denatured) - H00084299-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

XTP4 Overexpression Lysate (Native) - NBL1-08232 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: XTP4 Overexpression Lysate (Adult Normal) [NBL1-08232] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for XTP4.

C17orf37 Over-expression Lysate Product - GWB-3B92F6 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human MIEN1 Knockdown Stable Cell Line - CSC-DC009516 from Creative biogene

Category Cell Line
Species Human
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