Gene Symbol | MAP2K5 |
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Entrez Gene | 5607 |
Alt Symbol | HsT17454, MAPKK5, MEK5, PRKMK5 |
Species | Human |
Gene Type | protein-coding |
Description | mitogen-activated protein kinase kinase 5 |
Other Description | MAP kinase kinase 5|MAP kinase kinase MEK5b|MAPK/ERK kinase 5|MAPKK 5|MEK 5|dual specificity mitogen-activated protein kinase kinase 5 |
Swissprots | B4DE43 Q13163 Q92962 Q92961 |
Accessions | CBX51412 EAW77799 EAW77800 EAW77801 EAW77802 Q13163 AK024766 AK057521 BAG51927 AK293459 BAG56954 AK315435 BAG37823 BC008838 AAH08838 BI460343 BM682675 BT006780 AAP35426 CR542229 CAG47025 DN998338 JF432129 ADZ15346 U71087 AAB16851 U71088 AAB16852 XM_011521784 XP_011520086 XM_011521785 XP_011520087 XM_011521786 XP_011520088 XM_011521787 XP_011520089 XM_011521788 XP_011520090 NM_001206804 NP_001193733 NM_002757 NP_002748 NM_145160 NP_660143 NM_145161 NM_145162 |
Function | Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. {ECO:0000269|PubMed:7759517, ECO:0000269|PubMed:9384584}. |
Tissue Specificity | Expressed in many adult tissues. Abundant in heart and skeletal muscle. |
Top Pathways | Gap junction, MAPK signaling pathway, Neurotrophin signaling pathway, Oxytocin signaling pathway |
Human MEK5 full length protein - ab114459 from Abcam
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Human MEK5 protein fragment - ab159220 from Abcam
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MAP2K5 / MEK5 Antibody Blocking Peptide - LS-E3022 from LifeSpan Bioscience
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MAP2K5 / MEK5 Antibody Blocking Peptide - LS-E17734 from LifeSpan Bioscience
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MAP2K5 / MEK5 Antibody Blocking Peptide - LS-E9361 from LifeSpan Bioscience
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Recombinant Human MEK5 Protein - H00005607-P01 from Novus Biologicals
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Recombinant Human MEK5 Protein - H00005607-Q01 from Novus Biologicals
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MEK5 Peptide - P2883 from Novus Biologicals
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MEK5 Peptide - P2881 from Novus Biologicals
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MEK5 Peptide - P2880 from Novus Biologicals
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MAP2K5-Antibody-Center-T315-Blocking-Peptide - BP14316c from Abgent, a WuXi AppTec company
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MAP2K5-Antibody-S149-Blocking-peptide - BP7906f from Abgent, a WuXi AppTec company
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MEK5-MAP2K5-Antibody-S129-Blocking-peptide - BP7906d from Abgent, a WuXi AppTec company
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MEK5-Antibody-C-term-Blocking-Peptide - BP7906a from Abgent, a WuXi AppTec company
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Map2k5 Blocking Peptide - 33R-10402 from Fitzgerald
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MAP2K5 - H00005607-P01-10 from Acris Antibodies
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MAP2K5 - H00005607-P01-25 from Acris Antibodies
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MAP2K5 - H00005607-Q01-10 from Acris Antibodies
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MAP2K5 - H00005607-Q01-25 from Acris Antibodies
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MAP2K5 - P5586 from Acris Antibodies
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MAP2K5 fusion protein - ag8351 from Proteintech Group
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MAP2K5 fusion protein - ag8619 from Proteintech Group
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Recombinant Human MAP2K5 - MAP2K5-29560TH from Creative Biomart
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Recombinant Human MAP2K5 - MAP2K5-597H from Creative Biomart
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Recombinant Human Mitogen-Activated Protein Kinase kinase 5, His-tagged - MAP2K5-492H from Creative Biomart
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