MAP2K5

Gene Symbol MAP2K5
Entrez Gene 5607
Alt Symbol HsT17454, MAPKK5, MEK5, PRKMK5
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase kinase 5
Other Description MAP kinase kinase 5|MAP kinase kinase MEK5b|MAPK/ERK kinase 5|MAPKK 5|MEK 5|dual specificity mitogen-activated protein kinase kinase 5
Swissprots B4DE43 Q13163 Q92962 Q92961
Accessions CBX51412 EAW77799 EAW77800 EAW77801 EAW77802 Q13163 AK024766 AK057521 BAG51927 AK293459 BAG56954 AK315435 BAG37823 BC008838 AAH08838 BI460343 BM682675 BT006780 AAP35426 CR542229 CAG47025 DN998338 JF432129 ADZ15346 U71087 AAB16851 U71088 AAB16852 XM_011521784 XP_011520086 XM_011521785 XP_011520087 XM_011521786 XP_011520088 XM_011521787 XP_011520089 XM_011521788 XP_011520090 NM_001206804 NP_001193733 NM_002757 NP_002748 NM_145160 NP_660143 NM_145161 NM_145162
Function Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. {ECO:0000269|PubMed:7759517, ECO:0000269|PubMed:9384584}.
Tissue Specificity Expressed in many adult tissues. Abundant in heart and skeletal muscle.
Top Pathways Gap junction, MAPK signaling pathway, Neurotrophin signaling pathway, Oxytocin signaling pathway

MEK-5 (H-94) - sc-10795 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MEK-5 (H-94): sc-10795. Western blot analysis of MEK-5 expression in A-673 whole cell lysate.

MEK-5 (E-3) - sc-365198 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MEK-5 (E-3): sc-365198. Western blot analysis of MEK-5 expression in A549 whole cell lysate.

MEK-5 (C-20) - sc-1287 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MEK-5 (C-20): sc-1287. Western blot analysis of human recombinant MEK-5 fusion protein.

MEK-5 (R-18) - sc-9320 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MEK-5 (R-18): sc-9320. Western blot analysis of human recombinant MEK-5 fusion protein.

MEK-5 (21) - sc-135986 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
MEK-5 (21): sc-135986. Western blot analysis of MEK-5 expression in Jurkat whole cell lysate.

p-MEK-5 (Ser 311/Thr 315) - sc-135702 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
p-MEK-5 (Ser 311/Thr 315): sc-135702. Western blot analysis of MEK-5 phosphorylation in rat testis tissue extract. Blots were probed with p-MEK-5 (Ser 311/Thr 315): sc-135702 (A) and p-MEK-5 (Ser 311/Thr 315): sc-135702 preincubated with its cognate phosphorylated peptide (B).

p-MEK-5 (Ser 142) - sc-130203 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-MEK5 (phospho S311 + T315) antibody - ab70608 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEK5 (phospho S311 + T315) antibody (ab70608) at 1/1000 dilutionLane 1 : Whole cell lysates derived from EGF-stimulated A431Lane 2 : Whole cell lysates derived from EGF-stimulated A431 with immunising peptide

Anti-MEK5 antibody - ab69537 from Abcam

Prices $372.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MEK5 antibody - ab70611 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEK5 antibody (ab70611) at 1/1000 dilutionLane 1 : Whole cell lysates derived from mouse liverLane 2 : Negative control

Anti-MEK5 antibody - ab37775 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MEK5 antibody (ab37775) + Ramos cell lysateSecondaryHRP-anti-rabbitdeveloped using the ECL technique

Anti-MEK5 antibody - ab24828 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-MEK5 antibody - ab57725 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MEK5 antibody - ab57726 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MEK5 antibody - ab167383 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-MEK5 antibody (ab167383) at 1/500 dilutionLane 1 : MEK5 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

Anti-MEK5 antibody [EP648Y] - ab45146 from Abcam

Prices $392.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP648Y
Anti-MEK5 antibody [EP648Y] (ab45146) at 1/10000 dilution + HeLa cell lysate

Anti-MEK5 antibody - C-terminal - ab171760 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MEK5 antibody - C-terminal (ab171760) at 1/100 dilution + Mouse Neuro-2a cell line lysates at 35 µg

Anti-MAP2K5 / MEK5 Antibody (phospho-Ser311/Thr315) - LS-C33412 from LifeSpan Bioscience

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MAP2K5 / MEK5 Antibody (Ser311/Thr315) - LS-C33421 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-MAP2K5 / MEK5 Antibody (aa59-74) - LS-C63169 from LifeSpan Bioscience

Prices $245.00, $365.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MAP2K5 / MEK5 Antibody - LS-C182040 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP2K5 / MEK5 Antibody (phospho-Ser311/Thr315) - LS-C182320 from LifeSpan Bioscience

Prices $395.00
Sizes 25 µg
Host Rabbit
Clonality Polyclonal

Anti-MAP2K5 / MEK5 Antibody (aa384-412, AP) - LS-C223181 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP2K5 / MEK5 Antibody (aa384-412, APC) - LS-C223184 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP2K5 / MEK5 Antibody (aa384-412, Biotin) - LS-C223185 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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