MAP2K5

Gene Symbol	MAP2K5
Entrez Gene	5607
Alt Symbol	HsT17454, MAPKK5, MEK5, PRKMK5
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase 5
Other Description	MAP kinase kinase 5|MAP kinase kinase MEK5b|MAPK/ERK kinase 5|MAPKK 5|MEK 5|dual specificity mitogen-activated protein kinase kinase 5
Swissprots	B4DE43 Q13163 Q92962 Q92961
Accessions	CBX51412 EAW77799 EAW77800 EAW77801 EAW77802 Q13163 AK024766 AK057521 BAG51927 AK293459 BAG56954 AK315435 BAG37823 BC008838 AAH08838 BI460343 BM682675 BT006780 AAP35426 CR542229 CAG47025 DN998338 JF432129 ADZ15346 U71087 AAB16851 U71088 AAB16852 XM_011521784 XP_011520086 XM_011521785 XP_011520087 XM_011521786 XP_011520088 XM_011521787 XP_011520089 XM_011521788 XP_011520090 NM_001206804 NP_001193733 NM_002757 NP_002748 NM_145160 NP_660143 NM_145161 NM_145162
Function	Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. {ECO:0000269|PubMed:7759517, ECO:0000269|PubMed:9384584}.
Tissue Specificity	Expressed in many adult tissues. Abundant in heart and skeletal muscle.
Top Pathways	Gap junction, MAPK signaling pathway, Neurotrophin signaling pathway, Oxytocin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MEK-5 CRISPR/Cas9 KO Plasmid (h) - sc-401688 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-5 HDR Plasmid (h) - sc-401688-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-5 Double Nickase Plasmid (h) - sc-401688-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-5 Double Nickase Plasmid (h2) - sc-401688-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-5 CRISPR Activation Plasmid (h) - sc-401688-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-5 CRISPR Activation Plasmid (h2) - sc-401688-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-5 Lentiviral Activation Particles (h) - sc-401688-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-5 Lentiviral Activation Particles (h2) - sc-401688-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK-5 siRNA (h) - sc-35911 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK-5 shRNA Plasmid (h) - sc-35911-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK-5 shRNA (h) Lentiviral Particles - sc-35911-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK5 RNAi - H00005607-R06 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MEK5 RNAi - H00005607-R05 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MEK5 RNAi - H00005607-R08 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MEK5 RNAi - H00005607-R07 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU085441 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1109 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1110 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1108 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN12984 from Sigma-Aldrich Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12984 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MAP2K5 siRNA (Human) - CRH3777 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human MAP2K5 (NM_002757.3) - SHH337575 from Creative biogene Category siRNA Species Reactivities Human

Human MAP2K5 siRNA - orb264279 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MAP2K5 shRNA Plasmid (Human) - CHH3777 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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